Synopses & Reviews
The human genome is the key to what makes us human. Composed of the many different genes found in our cells, it defines our possibilities and limitations as members of the species. The ultimate goal of the pioneering project outlined in this book is to map our genome in detail -- an achievement that will revolutionize our understanding of human development and the expression of both our normal traits and our abnormal characteristics, such as disease. The Code of Codes
is a collective exploration of the substance and possible consequences of this project in relation to ethics, law, and society as well as to science, technology, and medicine.
The many debates on the human genome project are prompted in part by its extraordinary cost, which has raised questions about whether it represents the invasion of biology by the kind of Big Science symbolized by highenergy accelerators. While addressing these matters, this book recognizes that far more than money is at stake. Its intent is not to advance naive paeans for the project but to stimulate thought about the serious issues--scientific, social, and ethical--that it provokes. The Code of Codes comprises incisive essays by stellar figures in a variety of fields, including James D. Watson and Walter Gilbert and the social analysts of science Dorothy Nelkin and Evelyn Fox Keller. An authoritative review of the scientific underpinnings of the project is provided by Horace Freeland Judson, author of the bestselling Eighth Day of Creation.
, The book's broad and balanced coverage and the expertise of its contributors make The Code of Codes the most comprehensive and compelling exploration available on this historymaking project.
So far, the research (on human genetics) is on track, according to Kevles and Hood, who edited [this] impressive collection of thirteen critical essays by leading biologists, computer scientists and social scientists commenting on both the Genome Project itself and the important ethical implications of the new discoveries in human genetics. John Wilkes
The Code of Codes...gives a very balanced cross-section of views on both the scientific aspects of the project and many of the social issues surrounding it...In studying the human genome, much will be discovered about the evolution of life and living systems and if, as the book tries to show, there are fears, there is also hope that this knowledge will benefit humanity. What more can one want? Los Angeles Times
This book provides much valuable information on a program that has become international rather than provincial, but whose perceived urgency may exceed its justification. Sydney Brenner - Nature
The human genome defines our possibilities and limitations as members of the species. The ultimate goal of the pioneering project outlined in this book is to map our genome in detail. The Code of Codes is a collective exploration of the substance and possible consequences of this project in relation to ethics, law, and society as well as to science, technology, and medicine.
Includes bibliographical references (p. -374) and index.
About the Author
Daniel Kevles is the Stanley Woodward Professor of History and Law at Yale University.
Table of Contents
Part I History, Politics, and Genetics
1. Out of Eugenics: The Historical Politics of the Human Genome - Daniel J. Kevles
2. A History of the Science and Technology Behind Gene Mapping and Sequencing - Horace Freeland Judson
Part II Genetics, Technology, and Medicine
3. A Vision of the Grail - Walter Gilbert
4. The Challenges to Technology and Informatics - Charles Cantor
5. DNA-Based Medicine: Prevention and Therapy - C. Thomas Caskey
6. Biology and Medicine in the Twenty-First Century - Leroy Hood
7 A Personal View of the Project - James D. Watson
Part III Ethics, Law, And Society
8. The Social Power of Genetic Information - Dorothy Nelkin
9. DNA Fingerprinting: Science, Law, and the Ultimate Identifier - Eric Lander
10. Clairvoyance and Caution: Repercussions from the Human Genome Project - Nancy Wexler
11. Genetic Technology and Reproductive Choice: An Ethics for Autonomy - Ruth Schwartz Cowan
12. Health Insurance, Employment Discrimination, and the Genetics Revolution - Henry T. Greely
13. Nature, Nurture, and the Human Genome Project - Evelyn Fox Keller
14. Reflections - Daniel J. Kevles and Leroy Hood