Synopses & Reviews
The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena. This issue contains four highly detailed papers. The first paper focuses on quantitative aspects of the bgl operon for E.coli. The second contribution deals with ecosystem transitions affecting phenotype expressions and selection mechanisms. The third paper presents the Stochastic Calculus of Looping Sequences (SCLS) suitable for the description of microbiological systems, such as cellular pathways, and their evolution. The final contribution describes the use of biological transactions to make atomic sequences of interactions in the BlenX language.
Synopsis
This issue of the journal reports regular papers. The ?rst contribution is by ParasChopra and Andreas Bender and discusses quantitative modelling aspects of the bgl operon for E. coli. The second contribution is by Rodrick Wallace and Deborah Wallace and deals with ecosystem transitions a?ecting phenotype - pressions and selection mechanisms. The techniques used are statistical models. The thirdcontributionis byRoberto Barbuti, Andrea Maggiolo-Schettini, Paolo Milazzo, Paolo Tiberi and Angelo Troina and presents the Stochastic Calculus of Looping Sequences (SCLS) suitable for the description of microbiologicals- tems, such as cellular pathways, and their evolution. The last contribution is by Federica Ciocchetta and describes the use of biological transactions to make atomic sequences of interactions in the BlenX language. May 2008 Corrado Priami LNCS Transactions on Computational Systems Biology - Editorial Board Corrado Priami, Editor-in-chief University of Trento, Italy Charles Au?ray Genexpress, CNRS and Pierre & Marie Curie University, France Matthew Bellgard Murdoch University, Australia Soren Brunak Technical University of Denmark, Denmark Luca Cardelli Microsoft Research Cambridge, UK Zhu Chen Shanghai Institute of Hematology, China Vincent Danos CNRS, University of Paris VII, France Eytan Domany Center for Systems Biology, Weizmann Institute, Israel Walter Fontana Santa Fe Institute, USA Takashi Gojobori National Institute of Genetics, Japan Martijn A.