Synopses & Reviews
Transferring hematopoietic stem cells and immune cells has continued to be a promising therapeutic alternative and a fascinating area of cell biology as well as a field of persistent procedural problems. This explains why substantial parts of basic research on cell growth and differentiation, immune tolerance and antitumor effects, gene transfer, minimal residual disease and supportive care have settled around clinical transplantation in hematology and oncology. This second volume updates the current role of allogeneic and autologous transplantation in leukemias, lymphomas and solid cancers, including controversial strategies and novel experimental approaches. Outstanding representatives of leading groups guarantee first-hand information and indicate how we can work and cooperate more effectively to the benefit of our patients.
Table of Contents
From the contents:
Cellular Therapy: Targets and Effectors. Adoptive immunotherapy in chimeras.-
New Conditioning Strategies in Allogeneic Stem Cell Transplantation. Intensification of the conditioning regimen for patients with high-risk AML and MDS.-
Stem Cell Mobilisation, Processing and Characteristics. A "single"-delayed application of G-CSF after autologous peripheral blood stem cell transplantation.-
Cord Blood Transplantation. Lymphocyte subset reconstitution after cord blood transplantation.-
Mismatched Donor Transplantation. Bone marrow transplantation from mismatched unrelated donors.-
Clinical Transplantation - Hematologic Malignancies. Autografting and allografting for chronic lymphocytic leukemia.-
Clinical Transplantation - Solid Tumors. Autologous transplantation in breast cancer in Europe.-
Anti-angiogenesis. Angiogenesis inhibitor TNP-470 during bone marrow transplant and in minimal residual disease.-
Challenges in the Treatment of Fungal Infections.