Synopses & Reviews
Although more is known about sickle cell disease than about any other inherited disease, no cure for it exists. In America alone, about one in 375 who are of African ancestry is born with sickle cell disease. A smaller number of Americans descended from families from the Mediterranean area, the Middle East, and India also are affected. In addition, about eight percent of black Americans who do not suffer from the disease itself carry the gene for it that can be transmitted to their children.
Sickle cell disease is of enormous biological, social, and historic importance. It was first described in medical literature almost a century ago. Improvements during the past two decades in our understanding of the disease and in medical care are permitting those afflicted to live longer, more comfortable and more productive lives.
This book was written for all who are interested in this disease--those who have it, their families, the carriers of the sickle cell gene, teachers, and those who wish to update their information about it. This overview of sickle cell disease explains what it is and how it is inherited, as well as the relationship between the sickle cell gene and its geographic origins, the way the gene has been spread throughout history, and the effect of sickle cell hemoglobin on red blood cells that carry it.
Understanding Sickle Cell Disease describes the variety of symptoms in both children and adults and details the emotional aspects of the disease. Of particular interest is a chapter on the care, especially the home care, of those who are affected.
This book explains how it is possible today for couples carrying the genes to raise families free of the disease. Although there is no known cure for sickle cell disease, there is little doubt that one will ultimately be devised. This volume surveys current research efforts and the promise they hold.
For general readers a guide to understanding a debilitating genetic disease that affects tens of thousands who are of African heritage
Sickle Cell Disease and How It Is Inheritied * Who Has Sickle Cell Disease and Why * Inside the Red Blood Cell * Possible Effects of Sickle Cell Disease * How to Care for People with Sickle Cell Disease * Planning a Family * Searching for a Cure Although more is known about sickle cell disease than about any other inherited disease, no cure for it exists. It is of enormous biological, social, and historc importance. In America alone, about one in 375 who are of American ancestry is born with sickle cell disease. Since it was first identified in medical literature almost a century ago, its effects have been traced worldwide. This book was written for those who have the disease, their families, the carriers of the sickle cell gene, teachers, care givers, and those who wish to update their information. Included is discussion of the variety of symptoms in both children and adults as well as the emotional aspects of the disease. Of particular interest is a chapter on the care, especially the home care, of those who are affected. Here the reader is made aware of current research, the commitment to finding a cure, and the hope that one ultimately will be devised. Miriam Bloom is a geneticist who has written extensively on health issues for the federal government. A former senior editor for the Journal of the National Cancer Institute, she is president of SciWrite, an international biomedical writing and editing service.
Includes bibliographical references (p. -119) and index.