Synopses & Reviews
Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse’s normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.
Table of Contents
Normative Biology1. Gross Anatomy
2. Mouse Physiology
3. Reproductive Biology of the Laboratory Mouse
4. Endocrinology: Bone as a target tissue for hormonal regulation
5. Hematology of the Laboratory Mouse
6. Clinical Chemistry of the Laboratory Mouse
Management, Techniques, and Husbandry
7. Gnotobiotics
8. Management and Design: Breeding Facilities
9. Design and Management of Research Facilities for Mice
10. Nutrition
11. Health Delivery and Quality Assurance Programs for Mice
12. Environmental and Equipment Monitoring
13.
14. In Vivo Whole-Body Imaging of the Laboratory Mouse
Use of Mice in Biomedical Research
15. Behavioral Testing
16. Cardiovascular Disease: Mouse Models of Atherosclerosis
17. Convulsive Disorders
18. Eye Research
19. Genetic Analysis of Rodent Obesity and Diabetes
20. Mouse Models in Aging Research
21. Mouse Models of Inherited Human Neurodegenerative Disease
22. Mouse Skin Ectodermal Organs
23. Quality Control Testing of Biologicals