Diabetes mellitus is a complex, multifactorial disease that is often associated with progressive retinopathy and visual loss. In this book, Drs. Scott, Flynn, and Smiddy have compiled the current basic science and clinical information from leading authorities on diabetic eye disease. They have also included the results of clinical trials in patients with diabetic retinopathy, as well as the guidelines established by collaborative studies and the concepts of disease mechanisms and clinical management that have subsequently evolved from those guidelines. This monograph will provide practitioners with a concise, up-to-date, practical reference for the diagnosis and management of ocular disease in diabetic patients.
"This is a welcome second edition of the now classic text by Drs. Scott, Flynn, and Smiddy, renowned international authorities in the management of diabetic retinopathy and related ocular complications. The writing is clear and concise, highlights the core messages, and includes an extensive bibliography for additional reading by those who wish to probe further than the already comprehensive treatment provided in this text. Areas that will undoubtedly assume increasing importance, including telemedicine, anti-angiogenic strategies, and results from multi-center collaborative trials are well covered. This is a must-have volume for any ophthalmologist who sees patients with diabetes, regardless of subspecialty." -- Mark S. Blumenkranz, M.D., Professor and Chairman, Ophthalmology, Stanford University School of Medicine
"A masterpiece of the effects of diabetes on the eye that is both a practical guide as well as a useful reference for evidence based studies. Kudos to the editors for assembling a group of international experts in a comprehensive treatment of this topic!" -- Stanley Chang, M.D, Edward Harkness Eye Institute, New York
"This book is the definitive reference on ocular involvement from diabetes melliitus. The world's experts discuss pathophysiology, clinical manifestations,medical and surgical treatment and research frontiers of diabetic retinopathy . The various past, present, and future clinical trials on diabetic patients including an up to date review of newer studies and newer concepts are summarized for the reader.The writing is clear and succinct . This book is ideal for medical students, residents, fellows or practitioners." -- Lee Jampol , M.D., Louis Feinberg Professor, Department of Ophthalmology, Feinberg School of Medicine, Northwestern University
"This will be extremely useful to any ophthalmologist, concisely providing useful information on current, future, and past therapies communicated by leaders in the field. Undoubtedly, there have been changes in this field, particularly advances in therapies and imaging modalities, and this second edition is a welcome update of the first."--Doody's
"...an excellent text for those wishing to delve into this important topic in more detail." --Jama
Glossary
Ingrid U. Scott, MD, MPH and Harry W. Flynn, Jr., MD
Chapter 1: Medical Overview of the Worldwide Diabetes Epidemic
Robert E. Leonard II, MD and David W. Parke II, MD
Chapter 2: Classification of Diabetic Retinopathy
Charles P. Wilkinson, MD
Chapter 3: Histopathological Manifestations of Diabetic Retinopathy
Matthew Guess, MD and Sander R. Dubovy, MD
Chapter 4: Pathogenesis of Diabetic Retinopathy
Thomas W. Gardner, MD, MS and Lloyd Paul Aiello, MD, PhD
Chapter 5: Epidemiology and Risk Factors of Diabetic Retinopathy
Tien Y. Wong, MD, PhD, Ronald Klein, MD, MPH, and Barbara E. K. Klein, MD, MPH
Chapter 6: History of Evolving Treatments for Diabetic Retinopathy
George W. Blankenship, MD
Chapter 7: Photography, Angiography, and Ultrasonography in Diabetic Retinopathy
Andrew Lam, MD, Nicholas G. Anderson, MD, Carl D. Regillo, MD, and Gary C. Brown, MD, MBA
Chapter 8: Optical Coherence Tomography in the Management of Diabetic Retinopathy
Andrew A. Moshfeghi, MD, Ingrid U. Scott, MD, MPH, Harry W. Flynn, Jr., MD, and Carmen A. Puliafito, MD, MBA
Chapter 9: Clinical Studies on Treatment for Diabetic Retinopathy
Frederick L. Ferris III, MD, Matthew D. Davis, MD, Lloyd M. Aiello, MD, and Emily Y. Chew, MD
Chapter 10: Photocoagulation for Diabetic Macular Edema and Diabetic Retinopathy
Mitchell J. Goff, MD, H. Richard McDonald, MD, and Everett Ai, MD
Chapter 11: Vitrectomy for Diabetic Retinopathy
William E. Smiddy, MD and Harry W. Flynn, Jr., MD
Chapter 12: Intravitreal Pharmacotherapies for Diabetic Retinopathy
Sophie J. Bakri, MD and Peter K. Kaiser, MD
Chapter 13: Evolving Algorithms for Managing Diabetic Macular Edema
Diana V. Do, MD and Julia A. Haller, MD
Chapter 14: Management of Diabetic Retinopathy: Evidence-based Systematic Review
Quresh Mohamed, MD, Mark C. Gillies, MD, PhD, and Tien Y. Wong, MD, PhD
Chapter 15: Cataract Management in Diabetes
Mitchell S. Fineman, MD, William E. Benson, MD, Ingrid U. Scott, MD, MPH
Chapter 16: Nonretinal Ocular Abnormalities in Diabetes
Ingrid U. Scott, MD, MPH and Harry W. Flynn, Jr., MD
Chapter 17: The Effect of Systemic Conditions on Diabetic Retinopathy
Emily Y. Chew, MD
Chapter 18: Medical Management of the Diabetic Patient
Jay S. Skyler, MD
Chapter 19: Telemedicine for Diabetic Retinopathy
Helen K. Li, MD and Matthew T. S. Tennant, MD
Chapter 20: Future Therapies: Rationale for and Status of Anti-angiogenic and Anti-permeability Interventions
Nigel H. Timothy, MD, Jennifer K. Sun, MD, Jerry Cavallerano, OD, PhD, Thomas W. Gardner, MD, MS, and Lloyd Paul Aiello, MD, PhD
Appendix: Abstracts of Major Collaborative Multicenter Trials for Diabetic Retinopathy
Compiled by Nauman A. Chaudhry, MD, Ingrid U. Scott, MD, MPH, and Harry W. Flynn, Jr., MD
Index