Synopses & Reviews
The most up-to-date collection of immunology cases from world-class authorities in each disease entity
This book offers a comprehensive, cutting-edge selection of real-life case studies for in-depth investigation into the impact of immunology on modern medical diagnosis and treatment. Twenty-six case studieseffectively cover: immunodeficiency diseases, immediate hyper-sensitivity and mast cell disorders, autoimmune disorders, and malignancies of the lymphoid system. Each chapter presents a case study with a detailed background of the relevant immunological disorder, real data, references, and a conclusion, with interwoven discussion questions throughout. Each case study puts the individual patient into a larger context of the disease as it is seen in the patient population as a whole. Full-color photographs and illustrations complement the case studies, while a uniform presentation of the material across the book enhances readability.
This book offers medical students and professionals the complete tools necessary to understand and evaluate common clinical scenarios, and to teach these clinical conditions to others. It may be used alone or as a companion to the widely acclaimed Immunology: A Short Course, Sixth Edition (Wiley).
Review
"In all, while written as a clinically-relevant companion for an immunology text, this book can stand alone as a wonderful resource for any clinical immunologist and can serve as an excellent teaching aid for anyone studying immunology or training in a field that cares for patients with immune disorders." (The World Allergy Organization, 1 August 2011)“[This book] effectively accomplishes its stated goals. This well-written and easy-to-read book covers a wide variety of topics … and provides a wealth of experience in a patient-oriented format. The editors of this book succeed in moving readers from beginning to end using this case-based approach. [This book] offers a number of teaching possibilities and could be useful in teaching immunology when combined with current textbooks.” (JAMA, April 2010)
Synopsis
- 26 real-life cases illustrate the applications of basic immunology in clinical settings
- May be utilized alone or as a companion to Immunology: A Short Course 6th edition by Coico and Sunshine ISBN 9780470081587
- Each case study is introduced by clearly written descriptions of the major immunological disorders
- Full colour photographs and illustrations complement complete presentation of real data
- Includes complete set of problems and discussion questions for each chapter
Synopsis
- 26 real-life cases illustrate the applications of basic immunology in clinical settings
- May be utilized alone or as a companion to Immunology: A Short Course, 7th Edition by Richard Coico and Geofftry Sunshine (ISBN 9781118396919)
- Each case study is introduced by clearly written descriptions of the major immunological disorders
- Full colour photographs and illustrations complement complete presentation of real data
- Includes complete set of problems and discussion questions for each chapter
About the Author
Warren Strober, M.D., is Section Chief in the Laboratory of Clinical Investigation, Mucosal Immunity Section at the National Institute of Allergy and Infectious Diseases, National Institutes of Health.
Susan R.S. Gottesman, M.D., Ph.D., is Associate Professor in the Department of Pathology at SUNY Health Science Center at Brooklyn.
Table of Contents
Preface.
Dedication.
Introduction.
I. IMMUNODEFICENCY DISEASES.
Evaluation of the Immunodeficient Patient.
A. Primary Immunodeficiency Diseases.
1. X-linked Agammaglobulinemia (Bruton’s Agammaglobulinemia (Susan RS Gottesman).
2. Severe Combined Immunodeficiency Disease (Fabio Candotti).
3. DiGeorge Syndrome (Susan RS Gottesman).
4. Hyper-IgM Syndrome (Warren Strober).
5. Common Variable Immunodeficiency Disease (Warren Strober).
6. Autoimmune Lymphoproliferative Syndrome (ALPS) (Thomas Fleicher).
7. X-Linked Lymphoproliferative Disease (Jeffrey Cohen).
8. Hereditary Angioedema, (Milon Basta and Walter Reed).
B. Secondary Immunodeficiency Diseases.
9. Acquired Immunodeficiency Syndrome (AIDS) (Frank Maldarelli).
II. IMMEDIATE HYPERSENSITIVITY AND MAST CELL DISORDERS.
Introduction.
10. Mastocytosis (Cem Akin).
11. Anaphylaxis (Robert Hamilton).
12. Asthma (Dale Umetsu).
13. The Vasculitides (Michael Sneller).
III. AUTOIMMUNE DISORDERS.
Overview of Autoimmune Disorders and Mechanisms of Tolerance.
14. Myasthenia Gravis (Angela Vincent and John Radcliffe).
15. Multiple Sclerosis (Roland Martin).
16. Diabetes Mellitus (Kristina Rother).
17. Celiac Disease (Warren Strober).
18. Inflammatory Bowel Disease (Peter Mannon).
19. Psoriasis (Bruce Strober).
20. IgA Nephropathy and Kidney Transplantation (Roz Mannon).
21. Rheumatoid Arthritis (Barbara Mittleman).
22. Systemic Lupus Erythematosus (Gabor Illei).
23. Scleroderma (Atsushi Kitani).
IV. MALIGNANCIES OF THE LYMPHOID SYSTEM.
Classification of Lymphoid Malignancies.
24. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (Susan RS Gottesman).
25. Follicular Lymphoma (Susan RS Gottesman).
26. Plasma Cell Neoplasms (Susan RS Gottesman).
V. Appendix - Immunological Techniques Used in the Study of Patients with Disease.
Index.