Synopses & Reviews
An international group of scientists discuss the latest work on long-term potentiation (LTP), a model for encoding memory.
Synopsis
In this book, an international group of neurobiologists and psychologists discuss their latest findings and data which both support and challenge the long-term potentiation (LTP) model that suggests learning induces changes in communications between neurons. Essential reading for researchers and graduate students working in neuroscience, psychology and physiology.
Table of Contents
General Introduction: Long-term potentiation as a model for learning mechanisms: 'the story so far' Christian Hölscher; Part I. LTP In Vitro and in Vivo: How Can We Fine-Tune the Current Models for Memory Formation?: 1. Persisting with LTP as a memory mechanism: clues from variations in LTP maintenance Wickliffe C. Abraham; 2. LTP in the amygdala: implications for memory Michael T. Rogan, Marc G. Weisskopf, Yan-You Huang, Eric R. Kandel and Joseph E. LeDoux; 3. Multiple roles for synaptic plasticity in Pavlovian fear conditioning Stephen Maren; 4. Plasticity of the hippocampal cellular representation of space Kathryn J. Jeffrey; Part II. There is More to the Picture than LTP: Theta or Gamma Oscillations in the Brain and the Facilitation of Synaptic Plasticity: 5. Synaptic potentiation by natural patterns of activity in the hippocampus: implications for memory formation Fenella Pike, Sturla Molden, Ole Paulsen and Edvard I. Moser; 6. Plasticity in local neuronal circuits: in-vivo evidence from rat hippocampus and amygdala Mouna Maroun, Dan Yaniv and Gal Richter-Levin; 7. Theta-facilitated induction of LTP: a better model for memory formation? Christian Hölscher; 8. Neuronal processing of information in the neocortex and the role of gamma-oscillations in perception and memory formation Matthias H. J. Munk; Part III. Making Models from Empirical Data of Synaptic Plasticity: 9. Towards a physiological explanation of behavioural data on human memory: the role of theta-gamma oscillations and NMDAR-dependent LTP John Lisman, Ole Jensen and Michael Kahana; 10. Neuronal networks, synaptic plasticity, and memory systems in primates Edmund T. Rolls; 11. Revisiting the LTP orthodoxy: plasticity versus pathology Jill C. McEachern and Christopher A. Shaw; 12. Long-term potentiation and associative learning: can the mechanism subserve the process? Louis D. Matzel and Tracey J. Shors; Part IV. Setting the Stage for Memory Formation: Stress, Arousal and Attention: 13. Strategies for studying the role of LTP in spatial learning: what do we know? Where should we go? Donald P. Cain; 14. What studies in old rats tell us about the role of LTP in learning Gregory M. Rose and David M. Diamond; 15. Implications of the neuropsychology of anxiety for the functional role of LTP in the hippocampus Neill McNaughton; 16. Differential effects of stress on hippocampal and amygdaloid LTP: insight into the neurobiology of traumatic memories David M. Diamond, Collin R. Park, Michael J. Puls and Gregory M. Rose; Part V. Transgenic Mice as Tools to Unravel the Mechanisms of Memory Formation: 17. In vivo recording of single cells in behaving transgenic mice Yoon H. Cho and Howard B. Eichenbaum; 18. Understanding synaptic plasticity and learning through genetically modified animals Paul F. Chapman; 19. What can gene activation tell us about synaptic plasticity and the mechanisms underlying the encoding of the memory trace Sabrina Davis and Serge Laroche; Conclusions and future targets Christian Hölscher, Gal Richter-Levin and Timothy V. P. Bliss.