Synopses & Reviews
The thoroughly updated Third Edition of this acclaimed reference covers all aspects of pharmacology and physiology that are relevant to perioperative anesthetic management of patients. Tailored specifically to anesthesiologists' needs, the book provides the current information on drugs and organ functions that is essential for clinical decision-making.The Pharmacology section is organized by drug class and presents key facts on available agents, mechanisms of action, doses, benefits, risks, and drug interactions. The Physiology section, arranged by body system, explains how normal and abnormal body functions impact anesthetic management. This edition includes information on recently introduced and future drugs, new findings on uses and side effects of established agents, and new concepts on organ functions.Complementing the text are more than 600 diagrams--over 100 new to this edition--that clarify chemical structures, drug-induced responses, and physiologic mechanisms. More than 150 tables and a concise drug index are also included.
Synopsis
Dr. Stoelting's best-selling and highly acclaimed text, Pharmacology and Physiology in Anesthetic Practice, is now in its thoroughly updated Fourth Edition. In 60 concise, clearly written chapters, this book provides comprehensive, current, clinically oriented, authoritative information on all aspects of pharmacology and physiology that are relevant to perioperative patient management. This edition includes all new drugs and new findings on actions and interactions of established drugs.
More than 400 diagrams and more than 100 tables complement the text. This edition's new two-color page design will help readers spot key information. A separate drug index is included for quick reference.
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Table of Contents
SECTION I: PHARMACOLOGY 1 1 Pharmacokinetics and Pharmacodynamics of Injected and Inhaled Drugs 3
2 Inhaled Anesthetics 42
3 Opioid Agonists and Antagonists 87
4 Barbiturates 127
5 Benzodiazepines 140
6 Nonbarbiturate Intravenous Anesthetic Drugs 155
7 Local Anesthetics 179
8 Neuromuscular-Blocking Drugs 208
9 Anticholinesterase Drugs and Cholinergic Agonists 251
10 Anticholinergic Drugs 266
11 Cyclooxygenase-2 Inhibitors and Nonspecific Nonsteroidal Antiinflammatory Drugs 276
12 Sympathomimetics 292
13 Digitalis and Related Drugs 311
14 Alpha- and Beta-Adrenergic Receptor Antagonists 321
15 Antihypertensive Drugs 338
16 Peripheral Vasodilators, Nitric Oxide, and Nitrovasodilators 352
17 Cardiac Antidysrhythmic Drugs 370
18 Calcium-Channel Blockers 387
19 Drugs Used for Psychopharmacologic Therapy 398
20 Prostaglandins 420
21 Histamine and Histamine Receptor-Antagonists 429
22 Serotonin, Plasma Kinins, and Renin 444
23 Hormones as Drugs 456
24 Insulin and Oral Hypoglycemics 477
25 Diuretics 486
26 Antacids and Gastrointestinal Prokinetics 496
27 Anticoagulants 505
28 Antimicrobials 521
29 Chemotherapeutic Drugs 551
30 Antiepileptic Drugs 569
31 Drugs Used for Treatment of Parkinson Disease 580
32 Drug Treatment of Lipid Disorders 585
33 Central Nervous System Stimulants and Muscle Relaxants 591
34 Vitamins, Dietary Supplements, and Herbal Remedies 599
35 Minerals and Electrolytes 611
36 Blood Components, Substitutes and Hemostatic Drugs 623
37 Enteral and Parenteral Nutrition 635
38 Antiseptics and Disinfectants 640
SECTION II: PHYSIOLOGY 645
39 Cell Structure and Function 647
40 Body Fluids 658
41 Central Nervous System 663
42 Thermoregulation 668
43 Autonomic Nervous System 696
44 Pain 707
45 Systemic Circulation 718
46 Microcirculation and Lymphatics 735
47 Pulmonary Circulation 741
48 Heart 749
49 The Electrocardiogram and Analysis of Cardiac Dysrhythmias 761
50 The Lungs 771
51 Pulmonary Gas Exchange and Blood Transport of Gases 783
52 Acid-Base Balance 794
53 Endocrine System 803
54 Kidneys 817
55 Liver and Gastrointestinal Tract 831
56 Skeletal and Smooth Muscle 844
57 Erythrocytes and Leukocytes 849
58 Hemostasis and Blood Coagulation 859
59 Metabolism of Nutrients 863
60 Physiology of the Newborn and Elderly 871
Drug Index 883
Subject Index 000