Synopses & Reviews
Synopsis
This book presents the theoretical foundations of Systems Biology, as well as its application in studies on human hosts, pathogens and associated diseases.
This book presents several chapters written by renowned experts in the field. Some topics discussed in depth in this book include: computational modeling of multiresistant bacteria, systems biology of cancer, systems immunology, networks in systems biology.
Synopsis
PART I - Fundamentals 1 - Network Theory in Computational and Systems Biology: Concepts and Applications. Marcelo Ferreira da Costa Gomes, Bruna de Paula Fonseca e Fonseca, and Tatiana Martins Tilli
2 - In Search of an Organizing Principle in Biology: Thermodynamic Functions and Cancer. Edward Rietman and Jack A. Tuszynski
3 - Systems Immunology. Melissa Lever, Helder I Nakaya
4 - Mathematics and Computation for Modelling Transcriptional Regulatory Networks. Marcelo Trindade dos Santos, Ana Paula Nascimento, Fabr cio A. B. Silva
5 - Bio-modeling using Petri nets: A computational approach. Rafael Viana de Carvalho and Fons J. Verbeek
PART II - Applied Systems Biology
6 - The challenge of translating system biology in precision medicine of cancer. Alessandra Conforde, Milena Magalh es, Tatiana Tilli, Fabr cio Alves, Nicolas Carels
7 - Computational modeling of multiresistant bacteria. Fabricio A. B. Silva, Thiago Merigueti, Thiago Giannini, Rafaela Brum, Ana Paula Nascimento, Kele Belloze, Floriano Silva, Rodolpho Albano, Marcelo Trindade dos Santos, Maria Clicia Castro, M rcio Argollo and Ana Paula D'A. Carvalho-Assef
8 - Analysis Methods for Shotgun Metagenomics. Stephen Woloszynek, Gail Rosen, Zhengqiao Zhao, Dhantha Gunarathna, Alexandru Cristian, Joshua Chang Mell, Joshua P. Earl, Jacob Price, Christopher Sales
9 - ANOCVA: a non-parametric statistical test to compare clustering structures.
Alexandre Galv o Patriota, Davi Augusto Caetano de Jesus, and Andr Fujita
10 - A path from specific enzyme to metabolic pathway modeling to access target relevance in molecular inhibitor development. Larissa Catharina Costa, Nicolas Carels, Marcio Argollo de Menezes
11 - Mathematical-Computational Modeling in the Behavior Study of Neuronal Circuits of Repetitive Discharges. Maria Clicia Stelling de Castro, Dilson Silva, Celia Martins Cortez
Index