Synopses & Reviews
Synopsis
Knowledge of cholesterol and its interaction with protein molecules is of fundamental importance. This books examines the structural and functional aspects of the families of cholesterol-binding and cholesterol transport proteins.
Table of Contents
1. Cholesterol Protein Interaction: Methods and Cholesterol Reporter Molecules.- 2. Cholesterol in Alzheimer's Disease and other Amyloidogenic Disorders.- 3. Cholesterol-Binding Viral Proteins in Virus Entry and Morphogenesis.- 4. Sterol-protein interactions in cholesterol and bile acid synthesis.- 5. Cholesterol Oxidase: Structure and Function.- 6. Oxysterol binding proteins.- 7. High density lipoprotein structure-function and role in reverse cholesterol transport.- 8. Lipoprotein Modification and Macrophage Uptake: Role of Pathologic Cholesterol Transport in Atherogenesis.- 9. Cholesterol interaction with proteins that partition into membrane domains: an overview.- 10. Caveolin, Sterol Carrier Protein-2, Membrane Cholesterol-rich Microdomains and Intracellular Cholesterol Trafficking.- 11. Cholesterol in Niemann-Pick Type C disease.- 12. Protein Mediators of Sterol Transport Across Intestinal Brush Border Membrane.- 13. Cholesterol at the endoplasmic reticulum: roles of the sigma-1 receptor chaperone and implications thereof in human diseases.- 14. Prominin-1, a Distinct Cholesterol-Binding Membrane Protein, and the Organisation of the Apical Plasma Membrane of Epithelial Cells.- 15. Mammalian StAR-Related Lipid Transfer (START) Domains with Specificity for Cholesterol: Structural Conservation and Mechanism of Reversible Binding.- 16. Membrane Cholesterol in the Function and Organization of G-protein Coupled Receptors.- 17. Cholesterol effects on nicotinic acetylcholine receptor: Cellular Aspects.- 18. Cholesterol and Myelin Biogenesis.- 19. Cholesterol and Ion Channels.- 20. The cholesterol-dependent cytolysins family of Gram-positive bacterial toxins.- 21. Cholesterol Specificity of some Heptameric ß-Barrel Pore-forming Bacterial Toxins: Structural and Functional Aspects.- 22. Cholesterol-binding Toxins and Anti-cholesterol Antibodies as Structural Probes for Cholesterol Localization.- Index.