Hepatocellular Carcinoma and Liver Metastases: Diagnosis and Treatment

The state of the art concerning hepatocellular carcinoma and liver metastases is given in this review of the literature. The results of the author's analysis are frequently summarized in tables that are easy to understand. The book covers the broad range of possible diagnostic and management techniques: pathology, imaging, surgery, radiotherapy and chemotherapy. The gamut of indications, contra-indications, results and complications is discussed. Emphasis is placed particularly on catheter techniques.

Liver surgery has made extraordinary progress over the past 40 years, evolving from the first, timid partial resections in the 1950s to today's major resections and organ transplants. Examining the rea- sons for this progress, one cannot but be impressed by the substan- tial role that has been played by radiology. Formerly, preoperative planning was based on only nebulous scintigraphic scans. Today, surgeons have at their disposal a wide variety of radiological modalities for diagnosis and topography which are precise enough to exclude most operative surprises. Fur- thermore, the radiologist is becoming increasingly involved in ther- apy: prior to operation for tumor reduction by embolization and after resection for treatment of local complications - which could otherwise necessitate difficult and occasionally dangerous reoper- ations. As the author writes in his preface, it is not really astonishing that a radiologist is publishing a book on this topic, and he must be congratulated for his work-up, which combines important personal experience with a complete analysis of published papers on this topic.

Contents: Anatomy of the Liver.- Malignant Liver Lesions: Pathology.- Diagnosis and Staging of Malignant Liver Disease.- Surgical Treatment of Malignant Liver Lesions.- Radiotherapy.- Ethanol Injection Therapy of Liver Tumors.- Systemic Chemotherapy.- Selective Perfusion of Chemotherapeutic Agents.