Synopses & Reviews
The main problems and results of the therapy given to high-risk breast cancer patients are reviewed in this volume by leading investigators. Their approach assumes that a quantitative assessment of the risk has been made at diagnosis, which permits selective therapies for individual patients. This is the most effective way to avoid overtreating the low-risk and undertreating the high-risk patient.
The many advances in breast cancer research, as well as the large quantity of published material, make it very difficult to gain insight into the global aspects of cancer management. To follow and understand all the new developments is becoming a major challenge. For this reason, the editors decided to bring together a group of top researchers in breast cancer to provide a comprehensive, yet readable conceptual review of the state of the art of breast cancer diagnosis and therapy. The proposal to focus the review on the quantitative assessment of the risk at diagnosis, the determination of which may permit selective therapies for individual patients, was met with enthusiastic approval, resulting in the present volume with contributions by the leading investigators in the field. While the volume relating to diagnosis, published re- cently, focused on efforts leading to refinement at diagnosis of risk criteria sensitive enough to reliably distinguish the low- and high-risk categories, the second volume, by provid- ing a review of the main problems and results of therapy given to high-risk patients, can be considered as a continua- tion of the first book. A refined risk assessment at diagnosis and the application of the most suitable treatments to well- selected individuals are the most important steps towards avoiding the present worrisome reality of overtreating the low risk and undertreating the high-risk patients. The first few chapters of the present volume offer an insight into the general management of early breast cancer.
This volume continues the approach taken by the authors in a previous publication dealing with high-risk breast cancer. This second volume focuses on the therapy itself, whereas the first discussed how to evaluate the risk at diagnosis.
Table of Contents
Contents: Introduction.- General.- Surgery.- Radiotherapy.- Hormonal Therapy.- Chemotherapy-General.- Therapy-Adjuvant.- Chemotherapy-Metastatic.- Inflammatory Breast Cancer.- Stage III Breast Cancer.- Autologous Bone Marrow Transplantation.- Therapeutic Aspects of Tumor Biology Research.- Summary.- Subject Index.