Synopses & Reviews
This volume addresses the issues surrounding combination drug therapies and the treatment of HIV/AIDS. Each chapter, written by a leading researcher, provides the latest information on the pharmacology, clinical use - including adherence to treatment guidelines - prevention implications, mental health ramifications, and ethical and policy issues. By highlighting context as well as content, and focusing on general principles in addition to specific details, this necessary text remains relevant and valuable for future treatment advances.
Synopsis
AIDS is kind of like life, just speeded up. JavonP., heroinaddictwithAIDS, Bronx, NewYork, 1988 Now I m not so much scared of dying as scared of living. Mike D., heroin addict with AIDS, New Haven, Connecticut, 1998 Within little more than a decade, AIDS has been tranformed from an untreatable, rapidly fatal illness, into a manageable, chronic disease. Most of this tranformation has occurred in the past five years, accelerated by the advent of protease inhibitors and the proven benefits of combination antiretroviral therapy and prophylaxis against opportunistic infections. For people living with HIV/AIDS, these developments have offered unprecedented hope, and also new challenges. As reflected in the quotes above, some of the anxieties and anticipation of premature dying have been replaced by the uncertainties involved in living with a long-term, unpredictable illness. The role of caregivers for people with HIV/AIDS has also changed radically over this time. Earlier in the epidemic, we learned to accompany patients through illness, to bear witness, to advocate, to address issues of death, dying, and - reavement. The arrival of more effective therapy has brought with it new capabi- ties, but also new complexities, raising difficult problems concerning access to care, adherence, and toxicity."
Table of Contents
1. Combination Antiretroviral Chemotherapy: Shifting Paradigms and Evolving Praxis;
K.H. Mayer. 2. Pharmacokinetics of Protease Inhibitors and Drug Interactions with Psychoactive Drugs;
S.K. Chuck, et al. 3. Treatment Adherence to HIV Medications: The Achilles Heel of the New Therapeutics;
J.G. Rabkin, M. Chesney. 4. Combination Antiretroviral Therapies for HIV: Some Economic Considerations;
S.D. Pinkerton, D.R. Holtgrave. 5. Ethical Issues in the Use of New Treatment for HIV;
E. Heitman, M.W. Ross. 6. Mental Health Implications of new HIV Treatments;
S.C. Kalichman, B. Ramachandran. 7. Practical Prevention Issues;
D.G. Ostrow. 8. Postexposure Prophylaxis: A Community Member's Perspectives;
M. Shriver. 9. Behavioral Research Needs and Challenges of Nnew Treatments: AIDS as a Chronic Illness;
W. Pequegnat, E. Stover. Glossary. Index.