Section I. Basic Principles 1. Introduction, Bertram G. Katzung
2. Drug Receptors and Pharmacodynamics, Mark von Zastrow and Henry R. Bourne
3. Pharmacokinetics and Pharmacodynamics: Rational Dosing and the Time Course of Drug Action, Nicholas H.G. Holford
4. Drug Biotransformation, Maria Almira Correia
5. Development and Regulation of Drugs, Barry A. Berkowitz
Section II. Autonomic Drugs
6. Introduction to Autonomic Pharmacology, Bertram G. Katzung
7. Cholinoceptor-Activating and Cholinesterase-Inhibiting Drugs, Achilles J. Pappano
8. Cholinoceptor-Blocking Drugs, Achilles J. Pappano
9. Adrenoceptor Agonists and Sympathomimetic Drugs, Italo Biaggioni and David Robertson
10. Adrenoceptor Antagonist Drugs, David Robertson and Italo Biaggioni
Section III. Cardiovascular-Renal Drugs 11. Antihypertensive Agents, Neal L. Benowitz
12. Vasodilators and the Treatment of Angina Pectoris, Bertram G. Katzung and Kanu Chatterjee
13. Drugs Used in Heart Failure, Bertram Katzung and William W. Parmley
14. Agents Used in Cardiac Arrhythmias, Joseph R. Hume and Augustus O. Grant
15. Diuretic Agents, Harlan E. Ives
Section IV. Drugs With Important Actions on Smooth Muscle
16. Histamine, Serotonin, and the Ergot Alkaloids, Bertram G. Katzung
17. Vasoactive Peptides, Ian A. Reid
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, and Related Compounds, Emer M. Smyth and Garret A. FitzGerald
19. Nitric Oxide, Samie R. Jaffrey
20. Drugs Used in Asthma, Homer A. Boushey
Section V. Drugs That Act In The Central Nervous System
21. Introduction to the Pharmacology of CNS Drugs, Roger A. Nicoll
22. Sedative-Hypnotic Drugs, Anthony J. Trevor and Walter L. Way
23. The Alcohols, Susan B. Masters
24. Antiseizure Drugs, Roger J. Porter and Brian S. Meldrum
25. General Anesthetics, Paul F. White and Anthony J. Trevor
26. Local Anesthetics, Bertram G. Katzung and Paul F. White
27. Skeletal Muscle Relaxants, Paul F. White and Bertram G. Katzung
28. Pharmacologic Management of Parkinsonism and Other Movement Disorders, Michael J. Aminoff
29. Antipsychotic Agents and Lithium, Herbert Meltzer
30. Antidepressant Agents, Charles DeBattista
31. Opioid Analgesics and Antagonists, Mark A. Schumacher, Allan I. Basbaum, and Walter L. Way
32. Drugs of Abuse, Christian Luscher
Section VI. Drugs Used to Treat Diseases of the Blood, Inflammation, and Gout
33. Agents Used in Anemias; Hematopoietic Growth Factors, Susan B. Masters
34. Drugs Used in Disorders of Coagulation, James L. Zehnder
35. Agents Used in Dyslipidemia, Mary J. Malloy and John P. Kane
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, and Drugs Used in Gout, Daniel E. Furst, Robert W. Ulrich, and Cissy Varkey-Altamirano
Section VII. Endocrine Drugs
37. Hypothalamic and Pituitary Hormones, Susan B. Masters
38. Thyroid and Antithyroid Drugs, Betty J. Dong and Francis S. Greenspan
39. Adrenocorticosteroids and Adrenocortical Antagonists, George P. Chrousos
40. The Gonadal Hormones and Inhibitors, George P. Chrousos
41. Pancreatic Hormones and Antidiabetic Druigs, Martha S. Nolte
42. Agents That Affect Bone Mineral Homeostasis, Daniel D. Bikle
Section VIII. Chemotherapeutic Drugs
43. Beta-Lactam and Other Cell Wall- and Membrane Active Antibiotics, Henry F. Chambers and Daniel H. Deck
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, and Oxazolidinones, Henry F. Chambers and Daniel H. Deck
45. Aminoglycosides and Spectinomycin, Henry F. Chambers and Daniel H. Deck
46. Sulfonamides, Trimethoprim, and Quinolones, Henry F. Chambers and Daniel H. Deck
47. Antimycobacterial Drugs, Henry F. Chambers and Daniel H. Deck
48. Antifungal Agents, Don Sheppard and Harry W. Lampiris
49. Antiviral Agents, Sharon Safrin
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, and Sterilants, Henry F. Chambers and Daniel H. Deck
51. Clinical Use of Antimicrobial Agents, Harry W. Lampiris and Daniel S. Maddix
52. Antiprotozoal Drugs, Philip J. Rosenthal
53. Clinical Pharmacology of the Antihelminthic Drugs, Philip J. Rosenthal
54. Cancer Chemotherapy, Edward Chu and Alan C. Sartorelli
55. Immunopharmacology, Douglas F. Lake, Adrienne D. Briggs, and Emmanuel T. Akporiaye
Section IX. Toxicology
56. Introduction to Toxicology: Occupational and Environmental, Daniel T. Teitelbaum
57. Heavy Metal Intoxication and Chelators, Michael J. Kosnett 58. Management of the Poisoned Patient, Kent R. Olson
Section X. Special Topics
59. Special Aspects of Perinatal and Pediatric Pharmacology, Gideon Koren
60. Special Aspects of Geriatric Pharmacology, Bertram G. Katzung
61. Dermatologic Pharmacology, Dirk B. Robertson and Howard I. Maibach
62. Drugs Used in the Treatment of Gastrointestinal Diseases, Kenneth R. McQuaid
63. Therapeutic and Toxic Potential of Over-the-Counter Agents, Robin L. Corelli
64. Dietary Supplements and Herbal Medications, Cathi E. Dennehy and Candy Tsourounis
65. Rational Prescribing and Prescription Writing, Paul W. Lofholm and Bertram G. Katzung
66. Important Drug Interactions and Their Mechanisms, John R. Horn
Appendix: Vaccines, Immune Globulins, and Other Complex Biologic Products, Harry W. Palpiris and Daniel S. Maddix
Index