Synopses & Reviews
In Western societies, the incidence and prevalence of respiratory and food-related allergies have increased rapidly over the past decades. Changes in life style, e.g. in hygiene, child vaccination, housing insulation, food consumption patterns, etc. are thought to be involved in this increase. Direct and indirect costs related to allergy are expected to rise rapidly, especially in the Central and Eastern European countries that recently joined the European Union. Major concerns relate to the significant decrease of the quality of life of patients and their relatives. Therefore, time is urgent to develop strategies for large-scale and structural tackling of the allergy problem. Approaches aiming at allergy prevention with a focus on controlling our living environment and the food production chain, as well as on the choices consumers and patients make, seem very promising and complementary to solve this medicalized problem. This book, written by renowned experts, reflects the current ideas for future possibilities of allergy prevention, using integrated and multidisciplinary strategies and covering the entire knowledge framework from comprehensive fundamental research to implementation into society. It describes approaches from the following main topics: The medical and molecular context The food production chain and novel foods The living and occupational environment People and society. This book will be an indispensable tool for all those scientists that are searching for ways to solve the current allergy problems.
Synopsis
In Western societies the incidence and prevalence of respiratory and food-related allergies have increased rapidly over the past decades. Changes in life style are thought to be involved in this increase, namely hygiene, child vaccination, housing insulation and food consumption patterns. This book reflects the current ideas for future possibilities of allergy prevention, using integrated and multidisciplinary strategies and covering the entire knowledge framework from comprehensive fundamental research to implementation into society.
Table of Contents
Contents Preface Introduction 1. Future developments in allergy prevention: a matter of integrating medical, natural and social sciences Luud J.W.J. Gilissen, Harry J. Wichers, Huub F.J. Savelkoul and George Beers (The Netherlands) The medical and molecular context 2. Induction and regulation of allergen-specific IgE Prescilla V. Jeurink and Huub F.J. Savelkoul (The Netherlands) 3. Preventive vaccination against allergy: maternal allergen immunization protects offspring Ingrid Melkild, Berit Granum and Martinus Løvik (Norway) 4. Controlling processing in complex food systems: a potential route to food-allergy prevention E.N. Clare Mills, Neil M. Rigby, Ana I. Sancho, F. Javier Moreno and John A. Jenkins (UK) 5. Plant protein families as a basis for predicting the allergenicity of food proteins Peter R. Shewry, John Jenkins, Frederic Beaudoin and E.N. Clare Mills (UK) 6. Can cross-reactivity studies enable generic allergy prevention? Rosa Sánchez-Monge and Gabriel Salcedo (Spain) The food production chain and novel foods 7. The food production chain and novel foods: introduction Harry J. Wichers (The Netherlands) 8. Novel foods and novel processing techniques as threats and challenges to a hypersensitive world Hans Steinhart (Germany) 9. Tracking and tracing for allergen-free food production chains R.E. Poms and E. Anklam (Belgium) 10. Prediction of the potential allergenicity of novel proteins Gijs A. Kleter and Ad A.C.M. Peijnenburg (The Netherlands) 11. Production of hypoallergenic plant foods by selection, breeding and genetic modification Luud J.W.J. Gilissen, Suzanne T.H.P. Bolhaar, André C. Knulst, Laurian Zuidmeer, Ronald van Ree, Z.S. Gao and W. Eric van de Weg (The Netherlands) 12. In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch™ Mark W.E.J. Fiers, Gijs A. Kleter, Ad A.C.M. Peijnenburg, Herman Nijland, Jan Peter Nap and Roeland C.H.J. van Ham (The Netherlands) The living and occupational environment 13. Low-pollen-allergen ryegrasses: towards a continent free of hay fever? G. Spangenberg, N. Petrovska, G.A. Kearney and K.F. Smith (Australia) 14. Strategies for prevention and mitigation of hay fever M.F. Schenk, A.J.H. van Vliet, M.J.M. Smulders and L.J.W.J. Gilissen (The Netherlands) 15. Prevention of occupational allergies H. de Groot, G.C.M. Groenewoud, A.M.H. Bijl, N.W. de Jong, A. Burdorf, A.W. van Toorenenbergen, T. Blacquiere, C.C. Smeekens and R. Gerth van Wijk (The Netherlands) People and society 16. Allergy between the ears? Richard Shepherd (UK) 17. Economic impact of allergy prevention Miranda Mugford (UK) 18. Communication needs and food allergy: an analysis of stakeholder views Susan Miles (UK), Rene Crevel (UK), George Chryssochoidis (Greece), Lynn Frewer (The Netherlands), Kate Grimshaw (UK), Alicia Guidonet Riera (Spain), Hazel Gowland (UK), Rebecca Knibb (UK), Priska Koch (Switzerland), Charlotte Madson (Denmark), Clare Mills (UK), Susanna Palkonen (Finland), Sylvia Pfaff (Germany), Romana Roccaldo (Italy), Joachim Scholderer (Denmark), Oydis Ueland (Norway), Erkka Valovirta (Belgium) and Wim Verbeke (Belgium) 19. Allergy prevention: consumer perspectives David Reading (UK) 20. The patient's voice in allergy prevention Erkka Valovirta (Belgium)