Synopses & Reviews
Thoroughly updated and expanded, the second edition of this comprehensive textbook focuses on various aspects of events which occur at the tissue-biomaterial interface integrating current physiological knowledge of cell/tissue behavior and recent materials science/engineering developments in the field of biomaterials.
An Introduction to Tissue-Biomaterial Interactions, Second Editionconcentrates on fundamental concepts of wound healing process and interactions between the human body and implanted biomaterials or devices.
New to this edition are the expanded and detailed coverage of cell-biomaterial interactions and a section specifically addressing fundamental aspects of tissue engineering. Cell biology materials are carefully discussed throughout, presenting topics like cell receptors and the cytoskeleton, extracellular matrix production, and remodelling. Supplementary reading and activity suggestions are expanded.
An Introduction to Tissue-Biomaterial Interactions, Second Editionis accessible to students with minimal chemistry, biology, and advanced math knowledge. It is an invaluable resource for undergraduate students in biomedical engineering, as well as premedical students and engineering graduate students.
Praise for the First Edition:
"...well illustrated with a glossary, end-chapter summaries, and references...materials, scientists, medical device designers and manufacturers, corrosion researchers and practitioners, surgeons, and clinicians will profit from reading this book."CORROSION
"…a concise, topical, and not overly technical hardbound…the strengths of this book are its crisp information and condensed summaries. The jewels of this book are the diagrams and tables."Annals of Biomedical Engineering
"...delivers precisely what the authors intended...excellent book...great introduction...nicely complements existing texts..."Advanced Materials
Review
"...well illustrated with a glossary, end-chapter summaries, and references...materials, scientists, medical device designers and manufacturers, corrosion researchers and practitioners, surgeons, and clinicians will profit from reading this book." (
CORROSION, February 2006)
"…a concise, topical, and not overly technical hardbound…the strengths of this book are its crisp information and condensed summaries. The jewels of this book are the diagrams and tables." (Annals of Biomedical Engineering, Issue 31:11)
"...delivers precisely what the authors intended...excellent book...great introduction...nicely complements existing texts..." (Advanced Materials, Vol 16(4), 17 Feb 2004)
"This text would be of great use for faculty teaching courses on tissue-biomaterial interactions." (IEEE Engineering in Medicine and Biology, May/ June 2003)
"...a pleasure to read...highly recommendable..." (Biomateria.com)
"...excellent attention to detail…recommended for graduate students, faculty and researchers, and bioengineers and physicians." (Choice, Vol. 40, No. 6, February 2003)
Synopsis
The interaction of tissue and synthetic material can be the pivotal element in the artificial replacement of a body part damaged by disease or trauma. Hip replacements, dental implants, pacemaker leads, vascular grafts, heart valves, and dialysis machines all involve microscopic, tissue-level events that determine the success or failure of such devices. An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures.
Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body's wound-healing response is emphasized throughout. Specific topics covered include:
* Structure and properties of biomaterials
* Proteins
* Protein-surface interactions
* Blood-biomaterial interactions
* Inflammation and infection
* The immune system
* Biomaterial responses to implantation
* Biomaterial surface engineering
* Intimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions
The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix.
Ideal for a one-semester, biomedical engineering course, An Introduction to Tissue-Biomaterial Interactions provides a solid framework for understanding today's and tomorrow's implantable biomedical devices.
Synopsis
The interaction of tissue and synthetic material can be the pivotal element in the artificial replacement of a body part damaged by disease or trauma. Hip replacements, dental implants, pacemaker leads, vascular grafts, heart valves, and dialysis machines all involve microscopic, tissue-level events that determine the success or failure of such devices. An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures.
Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body s wound-healing response is emphasized throughout. Specific topics covered include:
- Structure and properties of biomaterials
- Proteins
- Protein-surface interactions
- Blood-biomaterial interactions
- Inflammation and infection
- The immune system
- Biomaterial responses to implantation
- Biomaterial surface engineering
- Intimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions
The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix.
Ideal for a one-semester, biomedical engineering course, An Introduction toTissue-Biomaterial Interactions provides a solid framework for understanding today s and tomorrow s implantable biomedical devices.
Synopsis
An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures. Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body’s wound-healing response is emphasized throughout. Specific topics covered include:Structure and properties of biomaterials
- Proteins
- Protein-surface interactions
- Blood-biomaterial interactions
- Inflammation and infection
- The immune system
- Biomaterial responses to implantation
- Biomaterial surface engineering
- Intimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions
The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix. Ideal for a one-semester, biomedical engineering course, An Introduction to Tissue-Biomaterial Interactions provides a solid framework for understanding today’s and tomorrow’s implantable biomedical devices.
Table of Contents
Preface.
Acknowledgments.
Introduction.
Biomaterials.
Proteins.
Protein-Surface Interactions.
Blood-Biomaterial Interactions and Coagulation.
Inflammation and Infection.
The Immune System and Inflammation.
Wound Healing.
Biomaterial Surface and the Physiological Environment.
Biocompatibility.
Example 1: Opening Occluded Vessels: Vascular Grafts, Intimal Hyperplasia.
Example 2: Replacing Joints and Teeth.
Answers to Quiz Questions.
Gloassry.
Index.