Synopses & Reviews
The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions. It provides a high profile and valuable publication resource on molecular mechanisms of cardiac remodeling for both the present and future generations of researchers, teachers, students and trainees.
Synopsis
This book examines the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last decades. It highlights areas needing further study, from key molecules and pathways to novel strategies.
Table of Contents
Part I: Molecular mechanisms of remodeling in pressure and volume overload hypertrophy and ehart failure.- β-adrenergic receptor signaling pathway in heart failure.- Remodeling of potassium channels in cardiac hypertrophy.- Role of gender in Ca2+ cycling and cardiac remodeling due to heart failure.- The failing heart: is it an inefficient engine or an engine out of fuel?.- Regulation of cardiac hypertrophic remodeling by the USP15/SLIM1 pathway.- Role of galectin-3 pathways in the pathogenesis of cardiac remodeling and heart failure.- A mitochondriocentric pathway to cardiomyocyte necrosis: