Synopses & Reviews
This book provides an authoritative review of developments in the chemistry of Beta-lactams: in particular the synthesis, reactivity and mechanisms of reaction, including novel Beta-lactam structures and non-Beta-lactam analogues.
Synopsis
The biosynthesis of Beta-lactums. Structure-activity relationships: Chemical. Structure-activity relationships: biological. The mechanisms of reactions of Beta-lactams. Mode of action: interaction with the penicillin binding proteins. Beta-Lactamase: mechanism of action. Beta-Lactamase: inhibition. Novel Beta-Lactam structures-the carbacephems . Non-Beta-Lactam mimics of Beta-lactam antibiotics. Classical Beta-Lactam structures. Index.