Synopses & Reviews
The Kiel classification of Non-Hodgkin lymphomas is an important tool for every histopathology laboratory! It leads to very exact differential diagnosis by distinguishing the various disease types from each other. In this updated second edition, the clear differentiation of T-cell lymphomas particularly stands out, as do the increased number of illustrations. The section dealing with immunohistochemistry has been completely rewritten by A.C. Feller. He compares the findings of monoclonal antibody investigations with the morphology. The clinical data and contribution on therapy build a bridge to the clinical treatment of malignant lymphoma. Yet throughout, the histological diagnosis and differential diagnosis remain the central focus of the book.
Review
From the reviews: "Dr. Alfred Feller and Dr. Jacques Diebold have presented us with succinct descriptions and high quality Giemsa-stained photomicrographs ... . Their most valuable contribution, however, is their discussion of unresolved problems of classification ... . The authors also bring attention to significant unresolved problems in the WHO classification, including thought-provoking discussions of ... . are to be congratulated for a job well done and for a most enjoyable and personal approach to the complex problems of lymphomas." (Maurice P. Barcos, Oncology Intl. J. Cancer Research and Treatment, Vol. 67(5-6), 2004) "Feller and Diebold's book is not only based on the WHO classification of lymphoma, but also mirrors its presentation ... . then follows something really good: a section specifically addressing, and indeed called, differential diagnosis. ... Another good feature of this book is its inclusion of organ-specific sections, for example, lymphoma of the lung ... . I liked this book. It is not simply a catalogue of lymphomatoid diseases. I think it will be practically useful." (Dr. D. Wright, ACP News, 2005)
Synopsis
The 1st Edition of Histopathology of Non-Hodgkin's Lymphomas, written in col- laboration with Professor H. STEIN and published in 1981, was received well and is now out of print. In the meantime, there has been an explosion of data that not only have made the definitions of various entities more precise but, above all, have confirmed the main entities originally delineated in the Kiel classification. The development of monoclonal antibodies and molecular cytogenetics has also made it possible to identify T-cell lymphomas more accurately. For example, many of the malignant lymphomas that were previously considered to be unclas- sifiable can now be included in a classification scheme that places the T-cell lymphomas alongside of the list of B-cell lymphomas. In 1988 the European Lymphoma Club published an "updated Kiel classification" (STANSFELD et al. 1988) based on this new knowledge. It includes a number of previously undefined types of T-cell lymphoma. Studies done in Japan (T. SUCH et al.) and China (L. Y Tu) have contributed to the understanding of these lymphoma types.
Table of Contents
History of lymphoma classification.- Current lymphoma classification.- Statistical data.- Nodal B-cell lymphomas; Nodal and leukemic T-cell lymphomas.- Extranodal lymphomas: Lymphomas of the GI tract; Lymphomas of the upper aerodigestive tract; Lymphomas of the larynx and trachea; Lymphomas of the salivery glands; Lymphomas of the eye, lacrimal glands and orbit; Lymphomas of the mediastinum; Lymphomas of the lung; Lymphomas of the pleura; Lymphomas of the heart; Lymphomas of the spleen; Lymphomas of the liver; Lymphomas of the reproductive system and urinary system; Lymphomas of the endocrine organs (thyroid, adrenal glands); Lymphomas of the skin; Lymphomas of soft tissue; Lymphomas of the bone; Lymphomas of the central nervous system; Intravascular B-cell lymphoma.- Plasma cell proliferations.- Lymphomas in immunocompromised patients.- Guidelines for lymphoma diagnosis in bone marrow.- Practical advice.