Synopses & Reviews
This widely used and highly praised textbook has been extensively revised to reflect the most exciting research across the entire range of neuroscience. A new feature is an introductory discussion of the mechanisms of gene regulation, while the superfamily of molecules responsible for
membrane signaling is given new emphasis as a unifying theme throughout molecular and cellular neurobiology. The roles of these molecules in impulse conduction and synaptic transmission are fully explained, and illustrated by computer models. For the first time in a neurobiology text, these
mechanisms can be explored by using a state-of-the-art interactive computer program provided with an accompanying tutorial handbook. In the sections dealing with neural systems, the comparative approach continues to be used to illustrate general principles. Students learn about the progress being
made toward a molecular basis for sensory perception and new methods for revealing the neural activity underlying sensory and motor functions are described. There is an emphasis on the plasticity of both sensory and the motor circuits in mediating functions that reflect the effects of activity or
recovery from injury. Central systems continue to be featured as the culmination of neural evolution. These include the systems vital for all animals, such as sleeping, feeding and reproduction, as well as the systems for language, emotion and higher cognitive functions that reach their peak in
humans. There is special emphasis on recent work on memory, contrasting the mechanisms for short-term working memory and long-term memory and summarizing the present understanding of the mechanisms oflong-term potential. The twin themes of organizational levels and comparative systems help bring
together the vast range of studies and provides a conceptual framework that unifies the field of neurobiology. As in previous editions, the text continues to draw on the advantages of having a single author. In addition, leaders in a number of specialties have assisted the author, so that the text
represents the most up-to-date views of current research on the nervous system.
Synopsis
This widely used and highly praised textbook has been extensively revised to reflect the most exciting research across the entire range of neuroscience. A new feature is an introductory discussion of the mechanisms of gene regulation, while the superfamily of molecules responsible for membrane signaling is given new emphasis as a unifying theme throughout molecular and cellular neurobiology. The roles of these molecules in impulse conduction and synaptic transmission are fully explained, and illustrated by computer models. For the first time in a neurobiology text, these mechanisms can be explored by using a state-of-the-art interactive computer program provided with an accompanying tutorial handbook. In the sections dealing with neural systems, the comparative approach continues to be used to illustrate general principles. Students learn about the progress being made toward a molecular basis for sensory perception and new methods for revealing the neural activity underlying sensory and motor functions are described. There is an emphasis on the plasticity of both sensory and the motor circuits in mediating functions that reflect the effects of activity or recovery from injury. Central systems continue to be featured as the culmination of neural evolution. These include the systems vital for all animals, such as sleeping, feeding and reproduction, as well as the systems for language, emotion and higher cognitive functions that reach their peak in humans. There is special emphasis on recent work on memory, contrasting the mechanisms for short-term working memory and long-term memory and summarizing the present understanding of the mechanisms of long-term potential. The twin themes of organizational levels and comparative systems help bring together the vast range of studies and provides a conceptual framework that unifies the field of neurobiology. As in previous editions, the text continues to draw on the advantages of having a single author. In addition, leaders in a number of specialties have assisted the author, so that the text represents the most up-to-date views of current research on the nervous system.
Synopsis
The second edition of this highly acclaimed textbook was thoroughly revised to incorporate a multitude of recent research findings in neuroscience. A new chapter on molecular neurobiology was added and the basic concepts of the synapse, impulse, neurotransmitters, and neuromodulators were put on a molecular basis. The author greatly extended the treatment of developmental and memory mechanisms and also introduced the field of neuroimmunology.
Description
Includes bibliographical references (p. 687-708) and indexes.
About the Author
About the Author Gordon M. Shepherd is Professor of Neuroscience at Yale University. He received his B.S. degree at Iowa State University, M.D. at Harvard Medical School, and Ph.D. at Oxford University. Dr. Shepherd is internationally known for his research on synaptic organization in the olfactory system and its relation to behavior.
Table of Contents
1. Introduction
PART I: Molecular and Cellular Mechanisms
2. Molecular Neurobiology
3. Neurons and Glia
4. The Membrane Potential
5. The Action Potential
6. The Synapse
7. Synaptic Potentials and Synaptic Integration
8. Second Messengers and Neuromodulators
9. Developmental Neurobiology
PART II: Sensory Systems
10. Introduction: From Receptors to Perceptions
11. Chemical Senses
12. The Somatic Senses
13. Muscle Sense and Kinesthesia
14. The sense of Balance
15. Hearing
16. Vision
PART III: Motor Systems
17. Introduction: The Nature of Motor Function
18. Autonomic Functions
19. Reflexes and Fixed Motor Responses
20. Locomotion
21. Motor Hierarchies
22. Manipulation
23. Communication and Speech
PART IV: Central Systems
24. Introduction: The Nature of Central Systems
25. Biorhythms
26. Visceral Brains: Feeding
27. Visceral Brains: Mating
28. Emotion
29. Learning and Memory
30. The Cerebral Cortex and Human Behavior