Synopses & Reviews
The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Annual Reports in Medicinal Chemistry series