Synopses & Reviews
This book contains an extensive collection of critical reviews, from leading researchers in the field of regulated protein degradation. It covers the role of regulated proteolysis in a range of microorganisms (from Gram positive, Gram negative and pathogenic bacteria to Archaea and the Baker's yeast Saccharomyces cerevisiae).
Table of Contents
Preface: Regulated proteolysis, from basic mechanism to pathogenicity; David A. Dougan Section A: AAA+ proteolytic machines 1. Machines of destruction - AAA+ proteases and the adaptors that control them; E. Gur, R. Ottofuelling & D.A. Dougan 2. The AAA+ protease Lon; E. Gur 3. FtsH protease-mediated regulation of various cellular functions; T. Okuno & T. Ogura Section B: Regulatory proteolysis in bacteria 4. Regulated proteolysis in Bacillus subtilis; N. Moliere & K. Turgay 5. Regulation of stress response pathways in Escherichia coli by proteolysis; D. Micevski &, D.A. Dougan 6. Regulation of the SigmaE stress response; S.E. Barchinger & S.E. Ades 7. Pathogenic bacteria: protein degradation and virulence; D. Frees, L. Brøndsted & H. Ingmer Section C: Regulated proteolysis in yeast 8. Roles of Cdc48 in regulated protein degradation in yeast; A. Buchberger 9. The role of AAA+ proteases in mitochondrial protein biogenesis, homeostasis & activity control; K.N. Truscott, L. Ward & W. Voos Section D: Ub-like protein modification and protein degradation in microorganisms 10. PUPylation and Mycobacteria; M. Samanovic, H. Li & K.H. Darwin 11. Archea proteasomes and SAMPylation; J.A. Maupin-Furlow