Synopses & Reviews
Biotechnology Second, Completely Revised Edition Edited by H.-J. Rehm and G. Reed in cooperation with A. Pühler and P. Stadler This fully revised and expanded Second Edition takes into account all recent developments in biotechnology. It is extraordinarily broad in scope, up-to-date, carefully structured and well-balanced. "Biotechnology" considers both basic concepts and widely-differing industrial applications: it is a successful synthesis of theory and practice. Any scientist aiming for success in industrial microbiology, biochemistry, molecular biology and chemical engineering must turn to "Biotechnology". Volume 8a: Biotransformations have developed into an important tool of organic synthesis. Volumes 8a and b provide a comprehensive guide to the established and emerging uses of enzymes and microorganisms. Each chapter is devoted to a single class of transformation so that the competing possibilities can be readily compared. Practical and reliable reactions are emphasized. Topics included in Volume 8a are: Practical Aspects Lipases Esterases Cleavage of Amide Bonds Nitriles Alkaloids Yeast/Alcohol Dehydrogenases Hydroxylation Flavin Monooxygenases Major topics of Volume 8b: Phosphorylation CarbonCarbon Bond Formation Glycosidation Flavin Monooxygenases
Synopsis
Biotransformations have developed into an important tool of organic synthesis. Most synthetic sequences will benefit from the use of a biotransformation step, and the use of multiple enzyme single pot reactions enables several steps to be telescoped together.
Volumes 8a and b provide a comprehensive guide to the established and emerging uses of enzymes. Each chapter is devoted to a single class of transformation so that the competing possibilities can be readily compared, and there is a strong emphasis on practical and reliable reactions.
Topics included in Volume 8a are: Perspectives/ Practical Aspects/ Lipases/ Esterases/ Cleavage of Amide Bonds/ Nitriles/ Alkaloids/ Yeast/ Alcohol Dehydrogenases/ Hydroxylation and Dihydroxylation/ Flavin Monooxygenases
Major topics of Volume 8b: Phosphorylation/ C-C Bond Formation/ Formation of Glycoside Bonds/ Synthetic Applications
Table of Contents
INTRODUCTION
Perspectives in Biotransformation
Practical Aspects
HYDROLASES
Biotransformations with Lipases
Esterases
Cleavage and Formation of Amide Bonds
Nitriles
REDOX ENZYMES
Alkaloids
Yeast
Dehydrogenases -
Characteristics, Design of Reaction Conditions, and Applications
Hydroxylation and Dihydroxylation
Flavin Monooxygenases -
Uses as Catalysts for Baeyer-Villiger Ring Expansion and Heteroatom Oxidation