Synopses & Reviews
The problem of chest pain with normal coronary arteriograms (`syndrome X') continues to represent a major challenge to contemporary cardiology. Progress has been made in recent years regarding the pathophysiology and management of this condition; however, information contained in the medical journals continues to be conflicting and controversial. This volume brings together leading authorities in the fields of chest pain and microvascular dysfunction. This book addresses specifically the cardiac causes of chest pain with normal coronary arteriograms and also the various extra-cardiac mechanisms known to play a role, including esophageal abnormalities, psychological conditions and the recently described `metabolic syndrome X'. Chest Pain with Normal Coronary Angiograms: Pathogenesis, Diagnosis and Management provides a comprehensive clinical and pathophysiological review of syndrome X. The whole spectrum of the syndrome is explored, including clinical features, mechanisms, diagnosis, treatment and prognosis.
Table of Contents
List of Contributors. Foreword. Preface. 1. Cardiac syndrome X and microvascular angina; J.C. Kaski. 2. Chest pain with normal coronary arteries: psychological aspects; S.G. Potts, C. Bass. 3. Esophageal chest pain; J.S. de Caestecker. 4. Esophageal abnormalities and `Linked - Angina' in syndrome X; A. Chauhan. 5. Abnormal pain processing in syndrome X; O. Frøbert, et al. 6. Insights into the pathophysiology of syndrome X obtained using positron emission tomography (PET); S.D. Rosen, P.G. Camici. 7. Myocardial metabolism in cardiac syndrome X; J.P. Bagger. 8. Endothelial dysfunction in cardiac syndrome X (microvascular angina); K. Egashira, et al. 9. Endothelin: an important mediator in the pathophysiology of syndrome X; I.D. Cox, J.C. Kaski. 10. Estrogen deficiency and syndrome X; P. Collins. 11. Alternative mechanisms for myocardial ischemia in syndrome X - New diagnostic markers; F. Crea, et al. 12. Increased plasma membrane ion-leakage: A new hypothesis for chest pain and normal coronary arteriograms; A. Waldenström, G. Ronquist. 13. A possible cell membrane defect in chronic fatigue syndrome and syndrome X; W.S. Watson, et al. 14. The changing concept of syndrome X; A. Maseri, et al. 15. Assessment of coronary blood flow reserve - Techniques and limitations; A. L'Abbate. 16. The role of echocardiography in diagnosis and management of cardiac syndrome X; P. Nihoyannopoulos. 17. Imaging in microvascular angina - what's new? A. Tweddel. 18. Assessment of quality of life in patients with syndrome X; F. Atienza, J.A. de Velasco. 19. Treatment of patients with angina and normal coronary arteriograms; G.M.C. Rosano, et al. 20. Management strategies for chest pain in patients with normal coronary angiograms; R.O. Cannon III. 21. Abnormal autonomic nervous control of the cardiovascular system; G.M.C. Rosano, et al. 22. The metabolic syndrome; F. Leyva, J.C. Stevenson. 23. Two syndromes X; A. Henderson. 24. Hyperlipidemia and endothelial vasodilator dysfunction: The pathogenetic link to myocardial ischemia; A.M. Zeiher. 25. Microvascular dysfunction in patients with systemic hypertension without left ventricular hypertrophy: The role of nitric oxide; J.A. Panza. 26. Microvascular angina and hypertensive left ventricular hypertrophy; W. Motz, S. Scheler. 27. Myocardial ischemia in hypertrophic cardiomyopathy: Clinical assessment and role in natural history; P.M. Elliott. 28. Microvascular endothelial dysfunction after heart transplantation; G. Vassalli, A. Gallino. Index.