Until now, those in need of information on infectious diseases had to choose between encyclopedic reference texts or the infectious diseases sections in standard textbooks in internal medicine. Now there is a better alternative-Clinical Infectious Diseases fills the long-standing need for a practical yet comprehensive work that offers easy, convenient access to the topic. Of interest to internists, infectious disease specialists, and residents in training, the book is structured to give the reader essential information about the etiology and pathogenesis of various infectious diseases, and focuses on the clinical issues of managing, diagnosing, and treating patients with all types of infection. The editors and contributors are internationally known and recognized experts, and aim to validate the increasingly universal approaches to the diagnosis and treatment of infections worldwide. Emphasizing the clinical presentation of the patient by organ-system, diagnostic considerations including geographic, anatomic and microbiologic concerns, are addressed in detail. Diagnostic algorithms are provided, and specific choices of antimicrobial therapy are discussed and compiled in a user-friendly tabular format. Preventive measures for different types of infections are also addressed. Sections devoted to infections in special patient/risk groups, such as the post operative patient, the patient with immunodeficiency, the trauma patient, and the burn patient are included, as well as coverage of infections of travelers to tropical countries, and patients who have been bitten or scratched by animals or insects. A detailed presentation on HIV infection includes discussions of epidemiology, pathogenesis, immunology, clinical manifestations and antiviral treatment, as well as management of opportunistic infections.
1. Historical Notes, Harold P. Lambert
2. Infectious Diseases: An Overview, Richard K. Root
I. Pathophysiology Of Infectious Diseases
3. Pathophysiology of Bacteria and Bacterial Diseases, David A. Relman
4. Pathophysiology of Viruses and Viral Diseases, David M. Koelle and Lawrence Corey
5. Introduction to Parasitic Protozoa and Helminths, Adel A.F. Mahmoud
6. Introduction to Fungi and Fungal Diseases, John E. Edwards, Jr. and Peter G. Pappas
7. Epidemiology of Clinical Infectious Diseases, Richard A. Goodman and James M. Hughes
8. Epidemiology and Control of Infectious Diseases in Health Care Facilities, Huan J. Chang and William Jarvis
9. Host Responses to Infection: Fever, Hyperthermia and Hypothermia, Richard K. Root
10. The Acute Inflammatory Response, Jan Verhoef
11. The Specific Immune Response, John M. Dwyer Response
II. Diagnostic Methods In Infectious Disease
12. Modern Imaging Techniques in Infectious Disease, Eric J. Stern, Hanh V. Nghiem, John F. Hiehle, Jr., and David H. Lewis
13. Hematologic Alterations in Infectious Disease Patients, Photis Beris and Francis A. Waldvogel
14. Metabolic and Endocrine Alterations in Infectious Disease Patients, Francis A. Waldvogel
15. Specimen Management and Rapid Detection of Infectious Agents, Fred C. Tenover
16. Clinical Bacteriology, James J. Plorde
17. Clinical Virology, Rhoda Ashley and Larry Corey
18. Clinical Mycology, Micheal A. Pfaller
19. Clinical Parasitology, James J. Plorde
20. Rickettsia and Chlamydia, W. Conrad Liles and Walter E. Stamm
III. Anti-Microbial Drugs: Principles and Usage
21. Mechanisms of Antimicrobial Action and Resistance, George A. Jacoby
22. Pharmacology of Antimicrobials, Sandra L. Preston and George L. Drusano
23. Antimicrobial Toxicities and Drug Interaction, James E. Leggett and S.R. Raber
24. Selection of Antimicrobials for Treatment, Jay P. Sanford
25. Outpatient Parenteral Therapy of Serious Infections, Alan D. Tice
26. Control of Antimicrobial Usage, Peter Davey
27. Penicillins, Catherine M.Creticos and John N. Sheagren
28. Cephalosporins, James B. Malow and John N. Sheagren
29. Other Beta-Lactam Antibiotics: Penems and Carpapenems, Monobactams, Pierre Tattevin, Guillaume Breton, and Claude Carbon
30. Aminoglycosides, David N. Gilbert
31. Glycopeptides, Adel Sulaiman, Robert M. Rakita, and Barbara E. Murray
32 Macrolides and Clindamycin, Howard S. Gold and Robert C. Moellering, Jr.
33. Tertracyclines and Chloramphenicol, Thomas M. Hooton
34. Fluoroquinolones, Ralf Stahlmann and Hartmut Lode
35. Sulfonamides and Trimethoprim, Stephen E. Sanche and Allan R. Ronald
36. Miscellaneous Antibacterial Drugs, Gordon Dow and Allan Ronald
37. Antimycobacterial Drugs, Charles A. Peloquin and Michael D. Iseman
38. Antimicrobial Therapy for Bacterial Diseases, David H. Spach and W. Conrad Liles
39. Antiviral Drugs and Therapy, Catherine Diamond and Lawrence Corey
40. Antiparasitic Drugs and Therapy, Keith Armitage
41. Antifungal Drugs, Peter G. Pappas and John Edwards
42. Selection of Antifungal Drugs for Deep Mycoses, Peter G. Pappas and John Edwards
IV. Vaccines And Immunomodulatory Agents
43. Principles of Vaccine Development and Immunoprophylaxis, Gordon Ada
44. Passive Immunoprophylaxis and Treatment, James E. Pennington
45. Specific Vaccines, Paul T. Heath and E. Richard Moxon
46. Growth Factors, Immunomodulators and Cytokines, Brigitta U. Mueller and Philip A. Pizzo
V. Infectious Disease Syndromes
47. Approach to the Patient with Fever: Acute Febrile Illness, Ethan Rubinstein and David Hassin
48. Fever in Hospitalized Patients, David N. Schwartz and Robert A. Weinstein
49. Fever of Unknown Origin, Richard K. Root and Robert G. Petersdorf
50. Bacteremia, Sepsis, and Septic Shock, Giorgio Zanetti, Jean-Daniel Baumgartner, and Michel-Pierre Glauser
51. Infections with Rash, Mort Swartz
52. Cellulitis and Abscesses, Dennis L. Stevens
53. Infectious Diseases with Lymphadenopathy or Lymphadenitis, Ivor Byren
54. Upper Respiratory Tract Infections, Charles B. Smith
55. Bronchitis and Bronchiectasis, C.M. Tang and C.P. Conlon
56. Acute Pneumonia, Feng Yee Chang and Victor L. Yu
57. Cavitary Pulmonary Disease, John L. Johnson and Jerrold J. Ellner
58. Diffuse Pulmonary Infiltrates and Acute Respiratory Distress Syndrome (ARDS), Kenneth P. Steinberg
59. Pleurisy and Empyema, H. Lode, T. Schaberg, J. Eller
60. Intraoral Infections, John S. Greenspan and Deborah Greenspan
61. Diarrhea and Gastroenteritis, Herbert L. DuPont and H. Irving Schweppe
62. Hepatitis, Margaret C. Shuhart and Robert L. Carithers, Jr.
63. Pyogenic Biliary Tract and Hepatic Infections, Jan V. Hirschmann
64. Infectious Complications of Pancreatitis, E. Patchen Dellinger
65. Peritonitis and Intra-abdominal Abscesses, E. Patchen Dellinger
66. Infective Endocarditis, Adolf W. Karchmer
67. Intravenous Catheter-related Infections, Suppurative Thrombophlebitis and Mycotic, Aneurysms: Diagnosis, Risk Factors, and Management
68. Myocarditis, Pericarditis, A. Martin Lerner
69. Acute and Chronic Urinary Tract Infections, Walter E. Stamm
70. Genital Herpes and Genital Ulcer Disease, H. Hunter Handsfield
71. Urethritis, Epididyimitis, Orchitis, Prostatitis, Kimberley K. Fox, Susan F. Isbey, Myron S. Cohen, and Culley C. Carson, III
72. Vulvovaginitis, Cervicitis, and Pelvic Inflammatory Disease (PID), Joanne Embree and R. Brunham
73. Meningitis, Young S. Kim and Martin G. Tauber
74. Encephalitis, R. Tyler Frizzell and Richard J. Whitley
75. Infections Associated with Myelopathy, Radiculopathy, and Neuropathy, Christina M. Marra
76. Focal Central Nervous System Infections, Allan R. Tunkel and W. Michael Scheld
77. Ocular and Periocular Infections, Annabelle A. Okada and Ann Sullivan Baker
78. Osteomyelitis, Jon T. Mader, Mauro Ortiz, and Jason H. Calhoun
79. Infectious and Post-Infectious Arthritis, Mekennon Abebe, Lee D. Kaufman, and Benjamin J. Luft
80. Myositis and Fasciitis, Dennis L. Stevens
81. Chronic Fatigue Syndrome, Dedra Buchwald
VI. Infections In Special Patient/Risk Groups
82. Post-Surgical Wound Infections, Ronald Lee Nichols
83. Burn Infections, Roberta Mann, Baiba J. Grube, David M. Heimbach
84. Infections Complicating Traumatic Injury, Wayne N. Campbell
85. Prosthetic Device Infections, Werner Zimmerli
86. Infection in the Immunodeficient Patient, M. Aoun and J. Klastersky
87. Infection in the Organ Transplant Recipient, Robert H. Rubin and Nina E. Tolkoff-Rubin
88. Hematopoietic Stem Cell Transplantation, Raleigh A. Bowden
89. Infection in the Malnourished Patient, Phillipe LePage, Achim Schwenk, Patrick De Mol, and Jean-Paul Butzler
90. Intravenous Drug Abuse and Infection, Christian Ruef
91. Alcohol Abuse, Host Defenses and Infection, Rob Roy MacGregor
92. Fever in Travelers to Tropical Countries, W. Conrad Liles and Wesley C. Van Voorhis
93. Diarrhea in Travelers to Tropical Countries, Herbert L. DuPont and H. Irving Schweppe
94. Eosinophilia in Travelers to Tropical Countries, Adel A.F. Mahmoud
95. Infections after Animal Bites and Scratches, Stephen J. Gluckman
96. Ectoparasite-Related Infections, David H. Spach and Karen M. Van de Velde
VII. HIV Infection and AIDS
97. Epidemiology and Prevention, Franoise Crabb, Marie Laga and Peter Piot
98. Pathogenesis: Molecular Biology and Virology of HIV, J. Michael Kilby and George M. Shaw
99. Immunology, Sharon A. Stranford and Jay A. Levy
100. Clinical Manifestations of HIV Infections and AIDS, Ann C. Collier, Christina M. Marra, and Lili A. Sacks
101. Antiretroviral Therapy, Lawrence Corey
102. Therapy of Opportunistic Infections, Jason I.N. Tokumoto and Harry Hollander
103. Vaccines, Dani P. Bolognesi