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Concepts of Genetics, Eleventh Edition emphasizes the fundamental ideas of genetics, while exploring modern techniques and applications of genetic analysis. The best-selling text has a strong problem-solving approach, and this edition has been extensively updated with relevant, cutting-edge coverage of emerging topics in genetics. The accompanying MasteringGenetics ™ online platform is updated with new tutorials and practice problems.
Synopsis
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Concepts of Genetics, Eleventh Edition emphasizes the fundamental ideas of genetics, while exploring modern techniques and applications of genetic analysis. The best-selling text has a strong problem-solving approach, and this edition has been extensively updated with relevant, cutting-edge coverage of emerging topics in genetics.
Note: You are purchasing a standalone product;MasteringGenetics™does not come packaged with this content. If you would like to purchase both the physical text and MasteringGenetics search for ISBN-10: 0321948475/ISBN-13: 9780321948472. That package includes ISBN-10: 0321948912/ISBN-13: 9780321948915 and ISBN-10: 0133863298/ISBN-13: 9780133863291.
MasteringGenetics is not a self-paced technology and should only be purchased when required by an instructor.
About the Author
William S. Klug is an Emeritus Professor of Biology at The College of New Jersey (formerly Trenton State College) in Ewing, New Jersey, where he served as Chair of the Biology Department for 17 years. He received his B.A. degree in Biology from Wabash College in Crawfordsville, Indiana, and his Ph.D. from Northwestern University in Evanston, Illinois. Prior to coming to The College of New Jersey, he was on the faculty of Wabash College as an Assistant Professor, where he first taught genetics, as well as general biology and electron microscopy. His research interests have involved ultrastructural and molecular genetic studies of development, utilizing oogenesis in Drosophila as a model system. He has taught the genetics course as well as the senior capstone seminar course in Human and Molecular Genetics to undergraduate biology majors for over four decades. He was the recipient in 2001 of the first annual teaching award given at The College of New Jersey, granted to the faculty member who “most challenges students to achieve high standards.” He also received the 2004 Outstanding Professor Award from Sigma Pi International, and in the same year, he was nominated as the Educator of the Year, an award given by the Research and Development Council of New Jersey.
Michael R. Cummings is Research Professor in the Department of Biological, Chemical, and Physical Sciences at Illinois Institute of Technology, Chicago, Illinois. For more than 25 years, he was a faculty member in the Department of Biological Sciences and in the Department of Molecular Genetics at the University of Illinois at Chicago. He has also served on the faculties of Northwestern University and Florida State University. He received his B.A. from St. Mary’s College in Winona, Minnesota, and his M.S. and Ph.D. from Northwestern University in Evanston, Illinois. In addition to this text and its companion volumes, he has also written textbooks in human genetics and general biology for nonmajors. His research interests center on the molecular organization and physical mapping of the heterochromatic regions of human acrocentric chromosomes. At the undergraduate level, he teaches courses in Mendelian and molecular genetics, human genetics, and general biology, and has received numerous awards for teaching excellence given by university faculty, student organizations, and graduating seniors.
Charlotte A. Spencer is a retired Associate Professor from the Department of Oncology at the University of Alberta in Edmonton, Alberta, Canada. She has also served as a faculty member in the Department of Biochemistry at the University of Alberta. She received her B.Sc. in Microbiology from the University of British Columbia and her Ph.D. in Genetics from the University of Alberta, followed by postdoctoral training at the Fred Hutchinson Cancer Research Center in Seattle, Washington. Her research interests involve the regulation of RNA polymerase II transcription in cancer cells, cells infected with DNA viruses, and cells traversing the mitotic phase of the cell cycle. She has taught courses in biochemistry, genetics, molecular biology, and oncology, at both undergraduate and graduate levels. In addition, she has written booklets in the Prentice Hall Exploring Biology series, which are aimed at the undergraduate nonmajor level.
Michael A. Palladino is Dean of the School of Science and Professor of Biology at Monmouth University in West Long Branch, New Jersey. He received his B.S. degree in Biology from Trenton State College (now known as The College of New Jersey) and his Ph.D. in Anatomy and Cell Biology from the University of Virginia. He directs an active laboratory of undergraduate student researchers studying molecular mechanisms involved in innate immunity of mammalian male reproductive organs and genes involved in oxygen homeostasis and ischemic injury of the testis. He has taught a wide range of courses for both majors and nonmajors and currently teaches genetics, biotechnology, endocrinology, and laboratory in cell and molecular biology. He has received several awards for research and teaching, including the 2009 Young Investigator Award of the American Society of Andrology, the 2005 Distinguished Teacher Award from Monmouth University, and the 2005 Caring Heart Award from the New Jersey Association for Biomedical Research. He is co-author of the undergraduate textbook Introduction to Biotechnology, Series Editor for the Benjamin Cummings Special Topics in Biology booklet series, and author of the first booklet in the series, Understanding the Human Genome Project.
Table of Contents
BRIEF CONTENTS Part One
Genes, ChromOsomes, and Heredity
1 Introduction to Genetics
2 Mitosis and Meiosis
3 Mendelian Genetics
4 Extensions of Mendelian Genetics
5 Chromosome Mapping in Eukaryotes
6 Genetic Analysis and Mapping in Bacteria and
Bacteriophages
7 Sex Determination and Sex Chromosomes
8 Chromosome Mutations: Variation in Number and Arrangement
9 Extranuclear Inheritance
Part Two
DNA: Structure, Replication, and Variation
10 DNA Structure and Analysis
11 DNA Replication and Recombination
12 DNA Organization in Chromosomes
Part Three
Gene Expression, Regulation, and Development
13 The Genetic Code and Transcription
14 Translation and Proteins
15 Gene Mutation, DNA Repair, and
Transposition
16 Regulation of Gene Expression in Prokaryotes
17 Regulation of Gene Expression in Eukaryotes
18 Developmental Genetics
19 Cancer and Regulation of the Cell Cycle
Part Four
Genomics
20 Recombinant DNA Technology
21 Genomics, Bioinformatics, and Proteomics
22 Applications and Ethics of Genetic Engineering and Biotechnology
Part Five
Genetics of Organisms and Populations
23 Quantitative Genetics and Multifactorial
Traits
24 Neurogenetics
25 Population and Evolutionary Genetics
Special Topics in Modern Genetics
1 Epigenetics
2 Emerging Roles of RNA
3 DNA Forensics
4 Genomics and Personalized Medicine
5 Genetically Modified Foods
6 Gene Therapy
Appendix A Selected Readings A-1
Appendix B Answers XX
Glossary G-1
Credits XX
Index XX