Synopses & Reviews
New epidemics such as AIDS and "mad cow" disease have dramatized the need to explore the factors underlying rapid viral evolution and emerging viruses. This comprehensive volume is the first to describe this multifaceted new field. It places viral evolution and emergence in a historical context, describes the interaction of viruses with hosts, and details the advances in molecular biology and epidemiology that have provided the tools necessary to track developing viral epidemics and to detect new viruses far more successfully than could be done in the recent past. This unique book also lucidly details case histories and offers practical suggestions for the prevention of future epidemics. The contributors are leading authorities in their disciplines, and were selected both for their expert knowledge and for their ability to define and elucidate the fundamental issues. The book is highly accessible and has been written for a wide audience that includes virologists, public health authorities, medical anthropologists, evolutionary biologists, geneticists, infectious disease specialists, and social scientists interested in medical and health issues.
Review
"Should appeal to a wide readership. It should be read by those responsible for curriculum design for medical and public health schools, by all professional workers dealing with infectious diseases, by biomedical writers responsible for informing the public, and by those responsible for determining
priorities for the funding of health programs and biomedical research and training." --The New England Journal of Medicine
"A fascinating and worrisome discussion....Due to the importance and general interest of the subject, readers at many levels of expertise will be fascinated by Emerging Viruses." --BioScience
Table of Contents
Foreword,
Richard M. Krause1. Viruses and Humankind: Intracellular Symbiosis and Evolutionary Competition, J. Lederberg
2. Examining the Origins of Emerging Viruses, S.S. Morse
PART I: Emergence in Historical Context
3. Patterns of Disease Emergence in History, W.H. McNeill
4. Influenza, R.G. Webster
5. Emerging Viruses in Context: An Overview of Viral Hemorrhagic Fevers, K.M. Johnson
PART II: Viruses and the Host
6. Ecology and Evolution of Host-Virus Association, R.M. May
7. Pathogenesis of Viral Infections, B.N. Fields
8. Virus and Cell: Determinants of Tissue Tropism, T.E. Shenk
PART III: Seeing the Unseen: Methods for Detecting Viruses
9. Virus Detection Systems, D.D. Richman
10. New Technologies for Virus Detection, D. Ward
PART IV: Tracking Emerging Viruses
11. Assessing Geographic and Transport Factors, and Recognition of New Viruses, R.E. Shope and A.S. Evans
12. Phylogenetic Moments in the AIDS Epidemic, G. Myers, K. MacInnes, and L. Myers
PART V: Ecological Sources of Emerging Viruses
13. Arthropod-Borne Viruses, T.P. Monath
14. Hantaan (Korean Hemorrhagic Fever) and Related Rodent Zoonoses, J. LeDuc, J.E. Childs, G.E. Glass, and A.J. Watson
15. Filoviruses, C.J. Peters et al.
PART VI: Interspecies Transfer: Case Studies of Animal Viruses tht Recently Crossed Species
16. Human Monkeypox, A Newly Discovered Human Virus Disease, Frank Fenner
17. Seal Plague Virus, B.W.J. Mahy
18. Canine Parvovirus, C.R. Parrish
PART VII: How Viruses Evolve: Variation and Evolution of RNA Viruses
19. Replication Error, Quasispecies Populations, and Extreme Evolution Rates of RNA Viruses, J. Holland
20. The High Rate of Retrovirus Variation Results in Rapid Evolution, H.M. Temin
21. Evolution of Influenza and RNA Viruses, P. Palese
22. Factors Restraining Emergence of New Influenza Viruses, B. Murphy
23. Recombination in the Evolution of RNA Viruses, J.H. Strauss
24. Evolutionary Relationships of Vectors and Viruses, B.F. Eldridge
PART VIII: Prospects for the Future
25. Global Change and Epidemiology: Nasty Synergies, T.E. Lovejoy
26. Are We Prepared for a Viral Epidemic Emergency?, L.J. Legters, L.H. Brink, and E.T. Takafuji
27. Surveillance Systems and Intergovernmental Cooperation, D.A. Henderson
28. Afterword: A Personal Summary Presented as a Guide for Discussion, E.D. Kilbourne