Synopses & Reviews
This new book is an up-to-date review of the clinical, epidemiological, and cytogenetic aspects of the fragile X (Martin-Bell) syndrome--the most common genetic cause of mental retardation after Down syndrome. The book includes the latest research findings concerning diagnosis on the basis of the appearance of a fragile site in cultured lymphocytes. It assumes little prior knowledge of the subject, and provides a clearly written, easy-to-understand discussion previously unavailable in a single reference source. The book will be of special interest to molecular biologists, cytogeneticists, medical geneticists, and clinicians and other professionals working with the mentally handicapped.
Table of Contents
1. X-Linked Mental Retardation and the Fragile X Syndrome: A Clinical Approach, J-P. Fryns
2. The Epidemiology of the Fragile X Syndrome, T. Webb
3. Behaviour and Treatment of the Fragile X Syndrome, R. Hagerman
4. DNA Studies of the Fragile X Mutation, W.T. Brown
5. Cytogenetics of the Fragile Cite at6 Xq27, N. Tommerup