PART I: MECHANISMS OF DISEASE.
1. Introduction to Disease.
Learning Objectives.
Disease Chronicle: The Black Death.
Introduction.
Manifestations of Disease.
Diagnosis.
Describing Disease.
Causes of Disease.
Chapter Summary.
Resources.
Interactive Activities.
2. Immunity, Inflammation, and Immune Disorders.
Learning Objectives.
Disease Chronicle: Inflammation.
Defense Mechanisms.
Hypersensitivity–Allergies.
Autoimmunity.
Immune Deficiency.
Vaccination.
Chapter Summary.
Resources.
Interactive Activities.
3. Infectious Diseases.
Learning Objectives.
Disease Chronicle: West Nile Virus.
Introduction.
Pathogenic Microorganisms.
Infection Prevention and Control.
Emerging Infectious Diseases.
Chapter Summary.
Resources.
Interactive Activities.
4. Neoplasms.
Learning Objectives.
Disease Chronicle: Cancer.
Introduction.
Benign Tumors.
Cancer.
Chapter Summary.
Resources.
Interactive Activities.
5. Hereditary Diseases.
Learning Objectives.
Disease Chronicle: President Lincoln and Marfan Syndrome.
Introduction to Heredity.
Transmission of Hereditary Diseases.
Abnormal Chromosome Diseases.
Sex Anomalies.
Genetic Counseling.
Congenital Diseases.
Chapter Summary.
Resources.
Interactive Activities.
6. Nutrition and Disease.
Learning Objectives.
Disease Chronicle: James Lind: A Treatise on Scurvy.
Nutrition.
Malnutrition.
Vitamin Deficiency, Excess, and Dependency.
Minerals.
Chapter Summary.
Resources.
Interactive Activities.
PART II: DISEASES OF THE SYSTEMS.
7. Diseases of the Cardiovascular.
System.
Learning Objectives.
Disease Chronicle: Dr. Christiaan Barnard.
Introduction to the Cardiovascular System.
Structure and Function of the Heart.
Structure and Function of the Blood Vessels.
Arteriosclerosis.
Atherosclerosis.
Diseases of the Heart.
Vascular Disease.
Hypertension.
Abnormalities of Heart Conduction.
Shock.
Age-Related Diseases.
Chapter Summary.
Resources.
Diseases at a Glance.
Interactive Activities.
8. Diseases of the Blood.
Learning Objectives.
Disease Chronicle: Four Body Humors.
Introduction.
Red Blood Cells.
Anemia.
Bleeding Disorders.
White Blood Cells.
Diagnostic Tests.
Chapter Summary.
Diseases at a Glance.
Interactive Activities.
9. Diseases of the Respiratory System.
Learning Objectives.
Disease Chronicle: Breathing and Clean Air.
Structure and Function of the Respiratory System.
Common Symptoms of Respiratory Disease.
Upper Respiratory Diseases.
Lower Respiratory Diseases.
Age-Related Diseases.
Diagnostic Procedures for Respiratory Diseases.
Chapter Summary.
Resources.
Diseases at a Glance.
Interactive Activities.
10. Diseases of the Digestive System.
Learning Objectives.
Disease Chronicle: Dysentery.
The Digestive System.
Diseases of the Mouth.
Diseases of the Esophagus.
Diseases of the Stomach.
Diseases of the Intestines.
General Disorders of the Digestive Tract.
Diseases Indicated by Stool Characteristics.
Functions of the Liver and Gallbladder.
Diseases of the Liver.
Diseases of the Gallbladder.
Structure and Function of the Pancreas.
Diseases of the Pancreas.
Age-Related Diseases.
Chapter Summary.
Resources.
Diseases at a Glance.
Interactive Activities.
11. Diseases of the Urinary System.
Learning Objectives.
Disease Chronicle: The Kidney Transplant.
Functions of the Kidney.
Diseases of the Kidney.
Diseases of the Urinary Bladder and Urethra.
Age-Related Diseases.
Diagnostic Tests and Procedures.
Chapter Summary.
Resources.
Diseases at a Glance.
Interactive Activities.
12. Diseases of the Reproductive System.
Learning Objectives.
Disease Chronicle: Tuskegee Institute Experiment.
Anatomy of the Female Reproductive System.
Physiology of the Female Reproductive System.
Diseases of the Female Reproductive Tract.
Neoplasms of the Female Reproductive Organs.
Abnormalities of Pregnancy.
Anatomy of the Male Reproductive System.
Physiology of the Female Reproductive System.
Diseases of the Male Reproductive System.
Sexually Transmitted Diseases.
Male and Female Infertility.
Sexual Dysfunction.
Age-Related Diseases.
Diagnostic Procedures for Reproductive Diseases.
Chapter Summary.
Resources.
Diseases at a Glance.
Interactive Activities.
13. Diseases of the Endocrine System.
Learning Objectives.
Disease Chronicle: Diabetes.
Functions of the Endocrine Glands.
Structure and Function of the Pituitary Gland.
Diseases of the Anterior Pituitary Gland.
Function of the Posterior Pituitary Gland.
Hyposecretion of the Posterior Pituitary Gland.
Structure and Function of the Thyroid Gland.
Diseases of the Thyroid Gland.
Structure and Function of the Adrenal Glands.
Diseases of the Adrenal Glands.
Structure and Function of the Parathyroids.
Diseases of the Parathyroid Gland.
Endocrine Function of the Pancreas.
Hyposecretion of the Pancreas.
Abnormalities in Secretion of Sex Hormones.
Age-Related Diseases.
Diagnostic Procedures for Endocrine Diseases.
Chapter Summary.
Resources.
Diseases at a Glance.
Interactive Activities.
14. Diseases of the Nervous System and Special Senses.
Learning Objectives.
Disease Chronicle: Phineas Gage and Neuroscience.
Structural Organization of the Nervous System.
Diseases of the Nervous System.
Infectious Diseases of the Nervous System.
Diseases of the Special Senses: Eye and Ear.
Degenerative Neural Diseases.
Convulsions.
Developmental Errors.
Brain Injury.
Stroke or Cerebrovascular Accident.
Traumatic Disorders.
Brain Tumors.
Cranial Nerve Disease.
Age-Related Diseases.
Diagnostic Procedures for the Nervous System.
Chapter Summary.
Resources.
Diseases at a Glance.
Interactive Activities.
15. Mental Illness.
Learning Objectives.
Disease Chronicle: Sybil.
Mental Illness.
Causes of Mental Illness.
Disorders Usually First Diagnosed.
in Infancy, Childhood, or Adolescence.
Developmental Disorders.
Substance Use Disorders.
Schizophrenia.
Mood Disorders.
Anxiety Disorders.
Eating Disorders.
Personality Disorders.
Suicide.
Diagnostic Tests for Mental Illness.
Chapter Summary.
Diseases at a Glance.
Resources.
Interactive Activities.
16. Diseases of the Bones, Joints, and Muscles.
Learning Objectives.
Disease Chronicle: Arthritis.
Interaction of Bones, Muscles, and Joints.
Structure and Function of Bones, Joints, and Muscles.
Diseases of the Bones.
Diseases of the Joints.
Diseases of the Muscles.
Age-Related Diseases.
Diagnostic Tests for Bone, Joint, and Muscle Diseases.
Chapter Summary.
Resources.
Diseases at a Glance.
Interactive Activities.
17. Diseases of the Skin.
Learning Objectives
Disease Chronicle: WW1 Soldiers.
Functions of the Skin.
Structure of the Skin.
Skin Lesions.
Infectious Skin Diseases.
Hypersensitivity or Immune Disorders of the Skin.
Benign Tumors.
Skin Cancer.
Sebaceous Gland Disorders.
Metabolic Skin Disorders.
Pigment Disorders.
Pressure Injuries of the Skin.
Thermal Skin Injuries.
Age-Related Diseases.
Diagnostic Procedures for Skin Diseases.
Chapter Summary.
Resources.
Interactive Activities.
Diseases at a Glance.
Glossary.
Answers to Interactive Activities.
Index.