Synopses & Reviews
This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This first volume is focused on the genetic and molecular basis of pathogenesis and the role of environmental factors triggering cardiovascular dysfunctions. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on recent advances in molecular and cellular pathophysiology. The book offers a valuable resource work for researchers in basic biomedical fields and clinical scientists alike, as well as guidelines for novel avenues of research in both basic pathophysiology and cardiovascular therapy and prevention.
Synopsis
This book offers a comprehensive exploration of the principles of cardiovascular epidemiology and molecular pathophysiology, including the unique aspect of outlining and discussing molecular concepts underlying epidemiological observations.
Synopsis
This book is aimed at introduction of the principles of both cardiovascular epidemiology and molecular pathophysiology including the unique aspect of outlining and discussing molecular concepts underlying epidemiological observations. Thereby it promotes and stimulates interdisciplinary concepts in the field of preventive medicine based on recent knowledge in molecular and cellular pathophysiology. This title is intended to serve as a knowledge base for both researchers in basic biomedical fields as well as clinical scientists and as a guideline towards novel avenues for research in both basic pathophysiology and cardiovascular therapy and prevention.
Table of Contents
Preface.- Introduction.- Basic epidemiology of cardiovascular disease.- Basic molecular pathophysiology of cardiovascular disease.- Primary risk factors.- Age.- Gender.- Ethinics.- Signaling molecules and genetic polymorphisms.- Diet and nutrition.- Physical activity.- Alcohol consumption.- Smoking.- Socioeconomics.- Stress and psychological factors.- Secondary risk factors.- Hypertension.- Obesity and diabetes.- Dyslipidemia.- Hyperuricaemia.- Biomarker and risk assessment.- Cardiovacular events.- Ischemic heart disease.- Stroke.- Heart failure.- Cardiac arrhythmias.- Pulmonary hypertension.- Peripheral arterial disease.- Thromboembolic complications.- Aortic aneurism.