Synopses & Reviews
Dr. W. B. Castle (1897-1990), who played a major role in the emergence of hematology as a scientific discipline in the first half of this century, was instrumental in establishing the world-widereputation of the Thorndike Memorial Laboratory and the Harvard Medical Unit at Boston City Hospital. In the first comprehensive biography of Castle, Anand Karnad highlights the golden age of medicine and hematology in Boston. Castle'searly experiments solved the puzzle of pernicious anemia and were the building blocks for a series of experiments on that disease that stand as one of the finest examples of clinical research ever conducted.
Castle and his group also made pioneering contributions to hemoglobin physiology, mechanisms of hemolysis, splenic function, and sickle cell anemia. Under his leadership, the Thorndike MemorialLaboratory attracted the best and the brightest talent, many of whom are present-day leaders in the world of medicine and science. Intrinsic Factorsis the story of Castle's life and work.
About the Author
A hematologist, Anand B. Karnadis Associate Professor of Medicine at the <>James H. Quillen College of Medicine, East Tennessee StateUniversity, Johnson City.
Table of Contents
Foreword
"A" In Chemistry: A Regular Habit
Gold-Headed Canes, Watchfobs, and Talk
Castle at the Birth of Modern Hematology
Horn Suit Qui Mal Y Pense
Boston City Hospital: Worth It--But Just!
Enthusiasm: To Be Inspired By A God
Professors Are a Strange Breed of People
At the Head of the Table
DistinguishedPhysician, Remarkable Man
Notes
Acknowledgments
Index