Synopses & Reviews
Ion channels are crucial components of living cells. Situated in the cell membrane, they allow ions to pass from one side of the membrane to the other. This book provides an overview of ion channel study, including up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction. Students of molecular biology, biochemistry, physiology, and neurobiology will benefit from this modern, concise text.
Review
"...[a] clear and concise introduction to the physics, chemistry, and molecular biology used for ion channel research...what distinguishes this book from standard textbooks is the inclusion of some details of the experimental design, so as to allow the reader to have a better feel of how the studies were done and how the abstract theories emerged from the data...The authors have done a fantastic job in presenting a balanced view and in pointing out unsettled areas." Lily Yeh Jan, Cell
Review
"...this book takes the reader to the frontiers of current research and should be of considerable interest to reproductive and developmental biologists." Ralph B.L. Gwatkin, Molecular Reproduction and Development
Review
"The new Ion Channels book by David J. Aidley and Peter R. Stanfield offers an easy and smooth initiation....The authors have done a fantastic job in presenting a balanced view and in pointing out unsettled areas." Lily Yeh Jan, Cell
Synopsis
Up-to-date introduction to ion channels and how they work, emphasising their molecular structure.
Synopsis
This undergraduate textbook provides an overview of ion channel study, including up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction.
Synopsis
Located in cell membranes, ion channels determine the passage of ions across them. Ion Channels examines the molecular structure of channels, which helps explain their permeability and selectivity, their gating and modulation, their responses to drugs and toxins, and the diseases caused when they do not function properly.
Table of Contents
Preface; 1. Introduction; 2. Ions on the move; 3. Investigating channel activity; 4. Molecular structures; 5. Permeability and selectivity; 6. Gating and modulation; 7. Drugs and toxins; 8. Dysfunctional channels in human disease; 9. Not the last word; References; Index.