Synopses & Reviews
Using the familiar
At A Glance format, the second edition of this best-seller takes the reader through a complete review course of metabolism in health and disease. The salient features of a metabolic pathway are highlighted on a detailed background map, offering the choice to absorb as much, or as little, of the available information as required.
The text has been updated to include inborn errors of metabolism and new chapters on porphyrins, cholesterol and sports/exercise metabolism. Another major feature is the extensively revised chapters on diabetes.
Metabolism At A Glance will be an invaluable aid to students requiring a knowledge of metabolism for undergraduate medical, biochemistry, veterinary, sports science and nutrition courses, and for biomedical scientists and clinicians specializing in diabetes and inborn errors of metabolism.
Review
"...a highly comprehensive set of notes and pathway maps concentrated exclusively on metabolism. If you are after an easy going metabolism book for revision or as a good reference guide, this would be the ideal choice, as it is not too daunting to read and had plenty of well-organised pathway maps to keep you busy. This is especially useful for first year medics as part of their foundation study revision"
Leech y Gelen, University of Wales College of Medicine"
‘The book is easy to follow as the salient features of each metabolic pathway are highlighted on a detailed background map…the more medical aspects will appeal especially to medical students as they correlate neatly the basic biochemical principles with the development of some metabolic diseases…the book would be of interest to undergraduates, postgraduates and lecturers preparing to lecture in the filed of metabolism.’
Biochemistry and Molecular Biology Education (Journal of)
Synopsis
For a quick and efficient way to review for exams, the At a Glance series is a must have. The visual format presents a comprehensive illustration on one side of the page and explanatory text on the other to give students a thorough understanding of the material. All key concepts are covered making the books in the At a Glance series ideal for students in need of an introductory review of a core subject.
Table of Contents
Foreword.
Preface.
1. Introduction to the Metabolic Pathways.
2. Biosynthesis of ATP I: ATP, the Molecule that Powers Metabolism.
3. Biosynthesis of ATP II: Mitochondrial Respiratory Chain.
4. The Oxidation of Cytosolic NADH+H+: The Malate/Aspartate Shuttle and the Glycerol Phosphate Shuttle.
5. Metabolism of Glucose to Provide Energy.
6. Metabolism of One Molecule of Glucose Yields 31 (or should it be 38?) Molecules of ATP.
7. Metabolism of Glucose of Glycogen.
8. Anaerobic Metabolism of Glucose and Glycogen to Yield Energy as ATP.
9. 2,3-Bisphosphoglycerate (2,3-BPG) and the Red Blood Cell.
10. Metabolism of Glucose to Fat (triacylglycerol).
11. Metabolism of Glucose to Fatty Acids and Triacylglycerol.
12. The Pentose Phosphate Pathway and the Production of NADPH+H+.
13. The Pyruvate/Malate Cycle and the Production of NADPH+H+.
14. Mammals Cannot Synthesize Glucose from Fatty Acids.
15. Metabolism of Triacylglycerol to Provide Energy as ATP.
16. The Ornithine Cycle for t5he Production of Urea: ‘the Urea Cycle.’.
17. Biosynthesis of the Non-Essential Amino Acids.
18. Catabolism of Amino Acids.
19. Catabolism of Amino Acids.
20. Metabolism of Amino Acids to Glucose in Starvation and During the Period Immediately after Refeeding.
21. Metabolism of Protein to Fat.
22. Disorders of Amino Acid Metabolism.
23. Amino Acid Metabolism, Folate Metabolism and the ‘1-Carbon Pool’ I: Purine Biosynthesis.
24. Amino Acid Metabolism, Folate Metabolism and the ‘1-Carbon Pool’ II: Pyrimidine Biosynthesis.
25. Porphyrin Metabolism, Haem and the Bile Pigments.
26. Glycogen Metabolism I.
27. Glycogen Metabolism II.
28. Glycogen Metabolism III: Regulation of Glycogen Breakdown.
29. Glycogen Metabolism IV: Regulation of Glycogen Synthesis.
30. Regulation of Glycolysis.
31. Regulation of Krebs Cycle.
32. Regulation of Gluconeogenesis.
33. Regulation of Fatty Acid Oxidation I: Mobilization of Fatty Acids from Storage in Adipose Tissue.
34. Regulation of Fatty Oxidation II: The Carnitine Shuttle.
35. The Ketone Bodies.
36. Ketone Body Utilization.
37. B-Oxidation of Unsaturated Fatty Acids.
38. Peroxisomal B-Oxidation.
39. Elongation and Desaturation of Fatty Acids.
40. Cholesterol, Bile Acids and the Steroid Hormones.
41. Metabolism of Ethanol.
42. Sorbitol, Galactitol, Glucuronate and Xylitol.
43. Fructose Metabolism.
44. Biochemistry of Sport and Exercise.
45. Diabetes I: Insulin-Stimulated Glycogen Synthesis-Signal Transductionj.
46. Diabetes II: Metabolism Changes in Type 1 Diabetes.
47. Diabetes III: Type 1 Diabetes, Type 2 Diabetes, MODY and Pancreatic B-Cell Metabolism.
48. Diabetes IV: Type 2 Diabetes and Insulin Resistance in Muscle and Adipose Tissue.
49. Diabetes V: Type 2 Diabetes and Insulin Resistance in Liver.
Index.