Synopses & Reviews
Preclinical research related to mood and anxiety disorders relies extensively upon mouse behavioral tests and models, the use of which continues to increase as a greater number of underlying susceptibility genes are discovered, new targets for medications are identified, and clinical studies reveal novel neurobiological risk factors.
Synopsis
This book offers a comprehensive resource for the behavioral approaches that are valuable for the characterization of mood and anxiety disorder-related behaviors in mice and the techniques that are utilized in the development of effective medications.
Table of Contents
1. Longitudinal Assessment of Deliberate Mouse Behavior in the Home Cage and Attached Environments: Relevance to Anxiety and Mood Disorders Martien J. Kas, Ilan Golani, Yoav Benjamini, Ehud Fonio, and Oliver Stiedl 2. Using Behavioral Patterns Across Species in Mood Disorder Research Jared W. Young and Mark A. Geyer 3. Telemetry in Mice: Applications in Studies of Stress and Anxiety Disorders Larry D. Sanford, Linghui Yang, and Laurie L. Wellman 4. Modeling Mouse Anxiety and Sensorimotor Integration: Phenotypes in the Suok Test Elisabeth Dow, Valerie Piet, Adam Stewart, Siddharth Gaikwad, Jonathan Cachat, Peter Hart, Nadine Wu, Evan Kyzar, Eli Utterback, Alan Newman, Molly Hook, Kathryn Rhymes, Dillon Carlos, and Allan V. Kalueff 5. Assessment of Social Approach Behavior in Mice Orsolya J. Kuti and Damon T. Page 6. The Mouse Defense Test Battery: A Model Measuring Different Facets of Anxiety-Related Behaviors Guy Griebel and Sandra Beeské 7. Novelty-Suppressed Feeding in the Mouse Benjamin Adam Samuels and Rene Hen 8. The Four-Plate Test in Mice