Synopses & Reviews
This is an important book on the role of neurodevelopmental factors in the pathogenesis of the major psychiatric disorders. An international group of experts, including many of those responsible for the ideas that have come to dominate current thinking, reviews the fields of developmental neurobiology, clinical psychiatry, and behavioral neuroscience. The first section, "The Developing Brain", reviews neurodevelopment from the molecular to the behavioral level. Section Two, "Development and Psychopathology", covers clinical applications of the basic principles of developmental neurobiology. The third and final section, "Integrative Models", presents approaches toward a synthesis of neurodevelopmental and clinical findings in psychiatric disorder.
Review
"This is an outstanding new book on the relationship between early developmental brain abnormalities and adult psychopathological states, integrating basic and clinical neurosciences. It is a welcome contribution to the field and will be useful as a reference for researchers and clinicians in psychiatry." Doody's Journal, Michael J. Schrift, DO
Review
"Taken as a whole, the authors collectively make a strong statement for the necessary integration of basic and clinical neurosciences, in understanding the emergence of psychopathology." Ricardo Berjano, MD; Neurological Research
Synopsis
International experts review neurodevelopmental factors underlying psychiatric disorder, and link these with clinical findings.
Synopsis
Neurodevelopmental factors in the pathogenesis of the major psychiatric disorders are reviewed by an international group of experts, including many of those responsible for the ideas that have come to dominate current thinking. The book considers neurodevelopment from the molecular to the behavioral level, covers clinical applications of the basic principles of developmental neurobiology, and presents approaches toward a synthesis of neurodevelopmental and clinical findings in psychiatric disorder.
Table of Contents
Part I. The Developing Brain: 1. Development of the cerebral cortex: an overview Jennifer S. Lund; 2. Development of the primate prefrontal cortex David A. Lewis; 3. The genetics of neurodevelopment and schizophrenia Astride M. Vicente and James L. Kennedy; 4. Glutamate receptors and development anomaly in medial temporal lobe in schizophrenia Robert W. Kerwin et al.; 5. MRI studies of developing brain Terry Jernigan and Elizabeth R. Sowell; 6.31P magnetic resonance spectroscopy studies of developing brain Jay W. Pettegrew et al.; 7. PET studies of developing brain Harry T. Chugani and Diane C. Chugani; 8. Long term effects of different early rearing experiences on social, emotional, and physiological development in nonhuman primates Stephen J. Suomi; Part II. Development and Psychopathology: 9. From birth to onset: a developmental perspective of schizophrenia in two national birth cohorts Peter Jones and D. John Done; 10. Developmental aspects of schizophrenia Michael F. Pogue-Geile; 11. Sex differences in schizophrenia Gretchen L. Haas and David J. Castle; 12. Psychopathology and brain dysfunction: structural imaging studies Shon Lewis; 13. Neuropathology, neurodevelopment, and schizophrenia Kathryn J. Kotrla et al.; 14. Neurodevelopmental models of affective disorders Henry A. Nasrallah; 15. Heterogeneity within obsessive compulsive disorder evidence for primary and neurodevelopmental subtypes Tom Blanes and Philip McGuire; 16. Schizophrenia: a critique from the devlopmental psychopathology perspectives Chris Hollis and Eric Taylor; Part III. Integrative Models: 17. Schizophrenia as an emergent disorder of late brain maturation Irwin Feinberg; 18. Schizophrenia as a developmental disorder of neural network integrity: the dysplastic net hypothesis Ed T. Bullmore et al.; 19. Neurodevelopment and schizophrenia: quo vadis? Matcheri S. Keshavan.