Synopses & Reviews
Synopsis
Preface.- A Brief History of Immunological Research into Psychosis and Pathways for Immune Influence of the Brain.-Basic Concept of Microglia Biology and Neuroinflammation in Relation to Psychiatry.- Epidemiological Studies of Prenatal and Childhood Infection and Schizophrenia.- Schizophrenia, Cytokines and Other Systemic Inflammatory Mediators to include oxidative stress and lymphocyte alterations].- Association between Schizophrenia, Microbial Infection and Microbiota.- Autoantibodies and psychosis.- Effect of Infection on Cognition in Schizophrenia and Healthy People.- Role of Infection, Autoimmunity, Atopic Disorders and the Immune System in Schizophrenia: Evidence from Epidemiological and Genetic Studies.- Microglial Activation and Psychotic Disorders: Evidence from Pre-clinical and Clinical Studies.- Early-Life Adversity, Systemic Inflammation, and Co-Morbid Physical and Psychiatric Illnesses of Adult Life.- Inflammation, Antipsychotic Drugs and Evidence for Effectiveness of Anti-inflammatory Agents in Schizophrenia.
Synopsis
Provides a comprehensive summary of the scientific evidence regarding the role of immune system in the pathogenesis and treatment of schizophrenia and related psychoses
Covers both basic science and clinical research
Supplies valuable recommendations for clinical practice and testable hypotheses for future research