Synopses & Reviews
This book is concerned with practical aspects of neuropathology and is aimed at practising general pathologists, forensic pathologists and neuropathologists. The emphasis is on subjects that are not well covered in standard pathology texts. The chapters provide guidelines on the investigation of head injury (including suspected non-accidential injury in children), sudden unexplained death in adults, prion diseases, infections and vascular diseases of the nervous system, CNS lymphomas, dementia, and disorders of nerve and muscle. All of the chapters include guidelines on the conduct of autopsies in these disorders and the book contains an appendix with clear diagrams and advice on the sampling of brain tissue at autopsy.
Synopsis
In commissioning this volume of Current Topics in Pathology, the editor of the series, Prof. Sir Colin Berry, asked me to produce something "which is aimed at the general pathologist but from the point of view of the neuropathologist who knows what is not being done well." This was easier said than done. Many aspects of neuropathology are encountered only infrequently in general pathology and are best dealt with by re- ferral of material to a specialist unit. Others need more extensive investigation than is practicable in a general pathology setting. Yet neurological disorders in general are common and are encountered by general histopathologists, paediatric and forensic pathologists on a daily basis, particularly in autopsy practice. In inviting contributions to this volume of Current Topics in Pathology, I therefore biased the con- tents towards disorders in which the conduct of the autopsy and the initial approach to neuropathological investigation are of critical importance in making the diagnosis. The authors all have a wealth of experience and expertise and I believe that this is reflected in their approach, which is both personal and practical. Indeed, the emphasis in this book is very much on the provision of practical advice. All of the chapters contain guidelines on the conduct of autopsies as well as infor- mation on the macroscopic and basic histological assessment of the nervous system in the relevant disorders.
Table of Contents
Autopsy appraoch to CNS infections. Cerebrovascular disease - practical issues in surgical and autopsy pathology.- Head injury in routine and forensic pathological practice.- Sudden unexplained death in adults.- Post-mortem investigation of dementia: a practical approach.- Investigation of prion diseases.- Autopsy investigation of disorders of skeletal muscle and peripheral nerves.- Lymphoma and the nervous system.- Appendix.