Synopses & Reviews
In Nutrition and Immunology: Principles and Practice, leading researchers and clinicians review the influence of diet on the immune system, and illuminate the extent to which diet-induced changes can contribute to the occurrence or prevention of selected diseases. Topics range from the quality of the immune response associated with nutrient deficiencies to the deterioration in the immune response resulting from select nutrient deficiencies. Also reviewed are the increased demand for antioxidant protection and tissue repair created by the consequences of immune activation, and the specific protein, vitamin, and lipid needs of the immune system. Extensive coverage is given to the impact of diet on such clinical issues as breast feeding, allergies, autoimmune diseases, cancer, perioperative condition, diabetes, allograft rejection, and oral disease. In all discussions the authors seek to clarify the complex interplay of nutrients in the modulation of the equally complex immune system. Nutrition and Immunology: Principles and Practice provides a comprehensive review of the role of nutrition in health, with a major focus on how diet can reduce the initial onset, as well as the progression, of numerous chronic diseases. Its state-of-the-art articles will help readers understand the molecular basis for improving health over the long term by defining the specific nutritional needs of the immune system throughout life, as well as during immunologic challenge, thus assuring the book's role as the new foundation reference in this dramatically developing field.
Review
". . .this book comes at a timely moment, when the impact of nutrition and immunology is being widely felt because of the AIDS epidemic. . .There are a number of novel areas treated in this book that illustrate the changing tide and the great need to understand the molecular basis of interactions, in addition to understanding and performing simple dietary assessment."-Foreword by Ranjit Kumar Chandra, DSc, PhD, MD "A wide range of topics are covered, beginning with chapters on nutritional assessment and nutrient requirements for a properly functioning immune system. The editors conclude with a series of discussions on nutrition and its role in a wide variety of clinical issues, ranging from a chapter on breast milk to the role of diet in various diseases. Chapters on alternative medicines and their effect on immunity are also included. This is a wealth of information that nutritionists, immunologists, and physicians may not always think about. Because of the many topics that are discussed, a large amount of information is provided in an accessible format with good references. . . Issues that are generally not included in immunology courses are compiled here, and probably should be. Most of the chapters are easy to read and contain some thought provoking material for discussion. This book could easily form the basis for a graduate level course.."-4 Stars!, Doody's Health Sciences Book Review Journal "This unique book, authored by leading investigators in the field of nutrition and immune function, is a comprehensive, readable collection for both researchers and clinicians...Ten basic science chapters review the stat-of-the-art with regard to specific nutrients and their impact on immunity...All of the basic science chapters have outstanding figures of metabolic pathways, and nicely summarize the current understanding of cellular mechanisms. The chapters that examine specific clinical issues include several noteworthy contributions, particularly the chapters on nutrition and common oral diseases, and several superb reviews of nutritional therapy approaches to inflammatory and autoimmune diseases. There are also excellent chapters on AIDS, cancer, diabetes, allograft rejection, food toxicology, nutrition/immunity interactions, perioperative feeding, immune consequences of breast feeding, and a review of antioxidants in the aging immune system...this well-written, authoritative, and comprehensive book is a welcome addition and valuable reference for clinicians and investigators interested in modifying immune responses through nutrition." -Quarterly Review of Biology "This is a substantial and well produced book in both physical and figurative senses, packed with information and references...provides a comprehensive review of the role of nutrition in health, with a major focus on how diet can reduce the onset and progression of numerous chronic diseases."-Nutrition and Health "...this text is outstanding. If focuses attention on science issues and provides clear, understandable summaries of the state of current knowledge ...The chapter on nutrition and immunity in aging is an excellent example of the comprehensive and authoritative coverage of the topics listed." - Food and Nutrition Bulletin "Of the recent books designed for this purpose, this text is outstanding. It focuses attention on science issues and provides clear, understandable summaries of the state of current knowledge....The chapter on nutrition and immunity in aging is an excellent example of the comprehensive and authoritative coverage of the topics listed." - Food and Nutrition Bulletin "With contributions by 67 authors the editors of "Nutrition and Immunology" try to classify and evaluate the enormous and complex flood of data as one the well-known relationship between nutrition and state of immunity.... Against the background of growing "food-design" the relationships between nutritional and immunological research reach a completely new dimension. In the opinion of the authors this will require the establishment of a new field of nutritional science: nutritional immunology, which will be based on interdisciplinary research....The strong point of the book is the convincing extensive discussion of mainly clinical findings on the relationship between nutrition and immunity." - Nahrung/Food
Synopsis
It is a pleasure to write the foreword to Nutrition and Table 1 Nutritional Status and Outcome of Infection Immunology: Principles and Practice. In fact, this book comes at a timely moment, when the impact of nutrition and Definite adverse outcome immunology is being widely felt because of the AIDS epi- Measles, diarrhea, tuberculosis demic. This is particularly of note in Africa, where large Probable adverse outcome HIV, malaria, pneumonia sums of money are being spent on nutritional intervention Little or no effect programs in the hopes of improving immune responsive- Poliomyelitis, tetanus, viral encephalitis ness. We should not forget, however, early advances in our Note: HIV= human immunodeficiency virus understanding of protein energy malnutrition (PEM). PEM can be used as a model to understand the nutritional basis of immunity, as well as the immunological influences on nutri- tional status. Despite advances in agricultural production, tance. However, both in vitro studies and tests in laboratory PEM continues to affect hundreds of millions ofthe world's animals may have little resemblance to what is experienced population. The functional impact of undernutrition varies in humans under field conditions. from mild morbidity to life-threatening infection.
Synopsis
A panel of leading researchers and clinicians review the influence of diet on the immune system, and illuminate the extent to which diet-induced changes contribute to the occurrence or prevention of selected diseases. Topics range from the role of mineral and cofactors in the transcriptional regulation of immune maturation to the deterioration of the immune system with select nutrient deficicencies. Also reviewed are the increased demand for antioxidant protection and tissue repair created by the consequences of immune activation, and the specific protein, vitamin, and lipid needs of the immune system. Extensive coverage is given to the impact of diet on such clinical issues as breast feeding, allergies, autoimmune diseases, cancer, perioperative condition, diabetes, allograft rejection, and oral disease. Nutrition and Immunology: Principles and Practice provides a comprehensive review of the role of nutrition in health, with a major focus on how diet can reduce the onset and progression of numerous chronic diseases.
Table of Contents
I. Nutritional Assesment. Application and Interpretation of Commonly Used Nutritional Assessment Techniques, Kenneth H. Brown. Evaluating Malnutrition: What Should the Physician Look For? Charles Halsted. Evaluation of the Immune System in the Nutritionally-at-Risk Host, Jonathan Powell, Andrea Borchers, Steven Yoshida, and M. Eric Gershwin. II. Specific Nutrient Requirements. (Normal Populations; Populations with Low Intakes, Including Teens, females, Elderly...). Caloric Intake: Sources, Deficiencies, and Excess - An Overview, Dean A. Troyer and Gabriel Fernandes. Protein and Amino Acids, Vernon R. Young. Specific Nutrient Requirements: Trace Elements, Janet C. King. Vitamins: Overview and Metabolic Functions, Robert Rucker. a-Lipoic Acid: The Metabolic Antioxidant, John K. Lodge and Lester Packer. Defining the Role of Dietary Phytochemicals in Modulating Human Immune Function, Harold Schmitz and Kati Chevaux. Dietary n-3 Polyunsaturated Fatty Acids Modulate T-Lymphocyte Activation: Clinical Relevance in Treating Diseases of Chronic Inflammation, Robert S. Chapkin, David N. McMurray, and Christopher A. Jolly. Nucleotides, George K. Grimble, Olwyn M. R. Westwood. III. Nutrient-Immune Interactions. Impact of Nutritional Status on Immune Integrity, Pam Fraker. Nutritional Modulation of Inflammation by Polyunsaturated Fatty Acids/Eicosanoids, Vincent A. Ziboh. IV. Clinical Issues. Immunological Considerations of Breast Milk, Bo Lonnerdal. Clinical Issues: Childhood Illnesses, Vaccinations, and Nutritional Status, Noel W. Solomons and Gerald T. Keusch. Protein Energy Malnutrition and Infectious Disease: Synergistic Interactions, Christopher A. Jolly and Gabriel Fernandes. Lipids, Inflammatory Cytokines, and Endothelial Cell Injury, Bernhard Hennig, Michal Toborek, and Gilbert A. Boissonneault. Nutrition and Allergy, Christopher Chang and M. Eric Gershwin. Adverse Reactions to Foods, Francesco Giuseppe Foschi, Lorenzo Marsigli, Francesco Chiappelli, Michelle A. Kung, Mauro Bernardi Giuseppe, and Francesco Stefanini. Perioperative Feeding: Nutrition and Immunity, Ronald R. Barbosa and Bruce M. Wolfe. Alcohol and Immune Function, Francesco Chiappelli, Michelle A. Kung, Giuseppe Francesco Stefanini, and Francesco Giuseppe Foschi. Cigaret Smoking, Substance Abuse, Nutritional Status, and Immune Function, Mari S. Golub. Nutrition, Immunity, and Alternative Medicine, Katherine Gundling, Andrea Borchers, and M. Eric Gershwin. Obesity and Immunity, Paul A. Davis and Judith S. Stern. Diabetes and Immunity, Manuel E. Baldeon and H. Rex Gaskins. Nutritional Modulation of Autoimmune Diseases, Claudio Galperin, Gabriel Fernandes, Ricardo M. Oliveira, and M. Eric Gershwin. Autoimmune Diseases of the Digestive Tract, Thomas P. Prindiville and Mary C. Cantrell. Diet and Allograft Rejection, Richard V. Perez and Steven Katznelson. Food Toxicology and Immunity, Linda Rasooly and Noel R. Rose. Interactions Between Nutrition and Immunity: Immunity Lessons from Animal Agriculture, Kirk C. Klasing and Tatiana V. Leshchinsky. Cancer and Nutrition, Carolyn K. Clifford. AIDS, William R. Beisel. Aging: Nutrition and Immunity, Simin Nikbin Meydani and Michelle Schelske Santos. Role of Nutrition in Common Oral Diseases, Cecilia Gorrel and Tiffany Bierer. The Anti Inflammatory Effects of Chinese Herbs, Plants, and Spices, Christopher Chang. The Influence of Probiotic Organisms on the Immune Response, Stephanie Blum, Yves Delneste, Anne Donnet, and Eduardo Jorge Schiffrin. Nutritional Effects on the Pathogen Genome and Phenotypic Expression of Disease. Melinda A. Beck. V. Future Directions. Whither Nutrition and Immunology Interactions Toward the Next Millennium? What is Past is Prologue, Noel W. Solomons. Index.