Synopses & Reviews
Salmonella enterica encompasses a diverse range of bacteria that cause a spectrum of diseases in many hosts. However, advancements in the prevention and treatment of its infections have been hampered by limited research efforts and lack of multidisciplinary approaches. This book covers a diverse range of relevant topics, including epidemiological and clinical aspects, molecular pathogenesis, and immunity to disease and vaccines. The book's up-to-date information on key aspects of salmonellosis in humans and animals, will interest graduate students and researchers, as well as clinicians.
Synopsis
Leading researchers discuss key aspects of the biology of Salmonella enterica infections in this broad-ranging book. S. enterica infects animals and humans, causing severe diseases in both. Some salmonellae can be transmitted from domestic animals to humans via the food chain and they therefore constitute a serious public health issue. This book will equip the reader with detailed and up-to-date knowledge on S. enterica giving an integrated view of clinical, molecular and immunological aspects of these infections.
Synopsis
Integrated view of clinical, molecular and immunological aspects of the biology of Salmonella enterica infections.
About the Author
Pietro Mastroeni is a Lecturer in the Department of Veterinary Medicine at the University of Cambridge, where he leads the Bacterial Immunology Team.Duncan Maskell is Professor of Microbiology and Head of the Department of Veterinary Medicine at the University of Cambridge.
Table of Contents
1. Epidemiological and clinical aspects of human typhoid fever Christopher M. Parry; 2. Antibiotic resistance in Salmonella infections Fiona J. Cooke and John Wain; 3. Host-specificity of Salmonella infections in animal species Timothy S. Wallis; 4. Public health aspects of Salmonella enterica in food production Tom Humphrey; 5. The Salmonella genome: a global view Anne L. Bishop, Gordon Dougan and Stephen Baker; 6. Pathogenicity islands and virulence of Salmonella enterica Michael Hensel; 7. In vivo identification, expression and function of Salmonella virulence genes Helen Andrews-Polymenis, Caleb W. Dorsey, Manuela Raffatellu and Andreas J. Bäumler; 8. Mechanisms of immunity to Salmonella infections Pietro Mastroeni; 9. Interactions of Salmonella enterica with phagocytic cells Bruce D. McCollister and Andres Vazquez-Torres; 10. Interactions between Salmonella and dendritic cells: what happens along the way? Cecilia Johansson, Malin Sundquist and Mary Jo Wick; 11. Immunity to Salmonella in domestic (food animal) species Paul Wigley, Paul Barrow and Bernardo Villarreal-Ramos; 12. Newer vaccines against typhoid fever and gastrointestinal Salmonelloses Richard A. Strugnell and Odilia L. C. Wijburg; 13. Salmonella enterica-based antigen delivery systems JoséA. Chabalgoity.