Synopses & Reviews
At the fourth Wiggers Bernard Conference, a group of 20 scientists from various fields discussed new findings relating to nitric oxide in shock, sepsis, and organ failure. It is now recognized that nitric oxide is induced by endotoxin and cytokines and plays a central role in infectious diseases, hemorrhage and ischemia. Intense discussions were held on the usefulness or danger of nitric oxide synthase inhibitors as well as on the application of exogenous nitric oxide or nitric oxide donors.
International experts examine the role of nitric oxide in various metabolic events such as septic shock, cardiovascular dysfunction, and trauma and hemorrhagic shock. The nitric oxide pathway and nitric oxide synthesis regulation are also discussed.