Synopses & Reviews
Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men.
Review
From the reviews: "This is a comprehensive and detailed presentation of the role of sperm chromatin in reproductive health and disease. ... Basic scientists in andrology, embryologists, and clinicians dedicated to the treatment of the infertile couple are the intended audience. The editors are field experts in the clinical and laboratory assessment of infertility ... . This work is unique in this field and it offers an excellent compilation of laboratory advances in the assessment of sperm health." (Irvin H. Hirsch, Doody's Review Service, December, 2011)
Table of Contents
I. Human Sperm Chromatin: Structure and Function
1. Sperm Chromatin: An Overview
Rodney Balhorn
2. Spermatogenesis: An Overview