Synopses & Reviews
Review
"In summary, this is not a cook book for either statisticians or mutageniticists. This book is a bridge between the two disciplines. It will help the statisticians to understand the problems the mutageniticists encounter in their experiments and help the latter converse fluently with the former to effectively interpret the outcomes of their experiments. Both statisticians and genetic toxicologists will benefit tremendously from this book and should have it on their desks." Journal of Toxicology and Environmental Health
Synopsis
This rigorous and practical account of the interpretation of mutagenicity test data draws upon the expertise of toxicologists and statisticians.
Table of Contents
Preface; 1. Introduction; 2. Microbial colony assays; 3. Mammalian cell colony assay; 4. Fluctuation tests; 5. In vitro cytogenetics; 6. Sister chromatid exchanges; 7. In vivo cytogenetics; 8. Dominant lethal test; 9. Drosophila; Appendices.