Synopses & Reviews
Thomas M. Devlin's
Textbook of Biochemistry with Clinical Correlationspresents the biochemistry of mammalian cells, relates events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to humans. Loaded with new material and chapters and brimming with detailed, full-color illustrations that clearly explain associated concepts, this sixth edition is an indispensable tool for students and professionals in the medical or health sciences.
Key Features of the Sixth Edition:
- Over 250 Clinical Correlations highlighting the significance of the biochemistry to clinical conditions and diseases
- MCAT-Style Questions with annontated answers in every chapter - in a format similar to that used by the National Board of Medical Examiners
- More than 1,200 high-quality, full-color illustrations
- A concise appendix reviewing important Organic Chemistry Concepts
New to the Sixth Edition:
- Fully Updated with a significant revision of all chapters and major topics
- Two new chapters: Fundamentals of Signal Transduction and Cell Cycle, Programmed Cell Death, and Cancer
- A Glossary that explains important biochemical terms New sections on the Basal Lamina Protein Complex and Molecular Motors
Review
"This textbook is a well used standard…appreciated by professionals." (
E-STREAMS, September 2007)
"This is an excellent teaching volume, which could readily be used not only be undergraduates and graduate students but also by fellows in clinical chemistry training programs." (Clinical Chemistry, October 2006)
"Recommended as a primary teaching text in Biochemistry courses: noted for its depth and organization, well-written and grand in scope, the chapters moving at a perfect pace to give the student a lasting lesson in the biochemical processes." (Electric Review, September/October 2006)
"...comprehensive and...appropriately updated. It should continue to help medical students see the relevance of biochemistry to medicine, which will only increase during their future careers. (Biochemistry and Molecular Biology Education, May/June 2006)
Review
"...a very readable text...ideal for medicine or clinical biochemistry undergraduate students...has much to offer to medicinal chemistry students..." (
Chemistry World, April 2004)
"Outstanding…classic...clear illustrations abound...an exceedingly thorough, accurate, and up-to-date volume." (The Quarterly Review of Biology)
"A delightful book to read…I would recommend this book highly...for any who seek to understand the biochemical basis of disease..." (Annals of Clinical Biochemistry)
"…I believe this text fills an important niche, and in that niche it is very well done…a very useful text for those going into medicine.” (Biochemistry and Molecular Education, July-August 2002)
"...a comprehensive biochemistry book...new material in key areas justifies the new edition..." (Doody's Health, April 19, 2002)
"There are numerous good textbooks available for general biochemistry, but medical, pharmacy, and other health professional students often question the relevance of the extensive coverage given to...simpler organisms...Devlin's textbook fills the needs of these students, with its strong emphasis on human biochemistry...an excellent choice for a pharmaceutical or medical biochemistry course." (Journal of Medicinal Chemistry, Vol. 45, No. 11)
"...This is a welcome and relatively inexpensive volume for students of biochemistry and especially those involved with clinical biochemistry".(Cell Biochemistry & Function, June 2003)
Synopsis
TEXTBOOK OF BIOCHEMISTRY WITH CLINICAL CORRELATIONS
Fifth Edition
Thomas M. Devlin
This newly revised and updated fifth edition of Devlin's Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at the cellular level to physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes.
This edition significantly expands the clinical correlation that highlight the significance of biochemistry to specific clinical problems. Full-color illustrations provide clear explanations for the concepts discussed, and end-of-chapter questions and answers act as challenging study material. Reorganized into five practical sections, Textbook of Biochemistry with Clinical Correlations covers these topics and much more:
* Structure of macromolecules-DNA, RNA, and protein structure
* Information transmission-replication, transcription, protein synthesis, and control of gene expression
* Functions of proteins-protein families, enzymes, membrane structure, and transport mechanisms
* Metabolic pathways and their control-carbohydrate, lipid, amino acid, and nucleotide metabolism
* Physiological processes-hormone and signal transduction, biochemistry of nervous tissue, muscle vision, coagulation and digestion, and principles of nutrition
Synopsis
This newly revised and updated fifth edition of Devlin’s Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at the cellular level to physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes.
This edition significantly expands the clinical correlation that highlight the significance of biochemistry to specific clinical problems. Full-color illustrations provide clear explanations for the concepts discussed, and end-of-chapter questions and answers act as challenging study material. Reorganized into five practical sections, Textbook of Biochemistry with Clinical Correlations covers these topics and much more:
- Structure of macromolecules–DNA, RNA, and protein structure
- Information transmission–replication, transcription, protein synthesis, and control of gene expression
- Functions of proteins–protein families, enzymes, membrane structure, and transport mechanisms
- Metabolic pathways and their control–carbohydrate, lipid, amino acid, and nucleotide metabolism
- Physiological processes–hormone and signal transduction, biochemistry of nervous tissue, muscle vision, coagulation and digestion, and principles of nutrition
About the Author
Thomas M. Devlin, Ph.D. - Professor Emeritus, Drexel University School of Medicine.
Table of Contents
PART I: STRUCTURE OF MACROMOLECULES.
1. Eukaryotic Cell Structure (T.M. Devlin).
2. DNA and RNA: Composition and Structure (S.A. Woski and F.J. Schmidt).
3. Proteins I: Composition and Structure (R.M. Schultz and M.N. Liebman).
PART II: TRANSMISSION OF INFORMATION.
4. DNA Replication, Recombination, and Repair (H.J. Edenberg).
5. RNA: Transcription and RNA Processing (F.J. Schmidt).
6. Protein Synthesis;
Translation and Posttranslational Modifications (D. Glitz).
7. Recombinant DNA and Biotechnology (G. Soslau).
8. Regulation of Gene Expression (D.L. Weeks and J.E. Donelson).
PART III: FUNCTIONS OF PROTEINS.
9. Proteins II: Structure-Function Relationships in Protein Families (R.M. Schultz and M.N. Liebman).
10. Enzymes: Classification, Kinetics, and Control (J.L. York).
11. The Cytochromes P450 and Nitric Oxide Synthases R.T. Okita and B.S.S. Masters).
12. Biological Membranes: Structure and Membrane Transport (T.M. Devlin).
PART IV: METABOLIC PATHWAYS AND THEIR CONTROL.
13. Bioenergetics and Oxidative Metabolism (D.S. Beattie).
14. Carbohydrate Metabolism I: Major Metabolic Pathways and Their Control (R.A. Harris).
15. Carbohydrate Metabolism II: Special Pathways and Glycoconjugates (N.B. Schwartz).
16. Lipid Metabolism I: Utilization and Storage of Energy in Lipid Form (J.D. McGarry).
17. Lipid Metabolism II: Pathways of Metabolism of Special Lipids (R.H. Glew).
18. Amino Acid Metabolism (M.W. Coomes).
19. Purine and Pyrimidine Nucleotide Metabolism (J.G. Cory).
20. Metabolic Interrelationships (R.A. Harris and D.W. Crabb).
PART V: PHYSIOLOGICAL PROCESSES.
21. Biochemistry of Hormones I: Polypeptide Hormones (G. litwach and T.J. Schmidt).
22. Biochemistry of Hormones II: Steroid Hormones (G. Litwack and T.J. Schmidt).
23. Molecular Cell Biology (T.E. Smith).
24. Iron and Heme Metabolism (W.M. Awad, jr.).
25. Digestion and Absorption of Nutritional Constituents (U. Hopfer).
26. Principles of Nutrition I: Macronutrients (S.G. Chaney).
27. Principles of Nutrition II: Micronutrients (S.G. Chaney).
Review of Organic Chemistry (C.N. Angstadt).
Appendix.
Index.