Synopses & Reviews
Well-known experts explore various aspects of the cellular environment of the retina, lens and cornea during normal and diseased states, including: - the extracellular matrix during corneal and vascular development; - the assessment of light damage from the environment and routine eye examinations; - the sources of oxidative damage and cellular protective measures; - the role of vitamin E therapy in retinopathy of prematurity. Professionals in ocular science, cell biology, developmental biology, neuroscience, and cell physiology will welcome the comprehensive discussion of the research frontiers. It will be of special interest to those concerned with the biochemical bases for degenerative eye diseases.
Synopsis
The eye has fascinated scientists from the earliest days of biological in- vestigation. The diversity of its parts and the precision of their interaction make it a favorite model system for a variety of developmental studies. The eye is a particularly valuable experimental system not only because its tissues provide examples of fundamental processes, but also because it is a prominent and easily accessible structure at very early embryonic ages. In order to provide an open forum for investigators working on all aspects of ocular development, a series of symposia on ocular and visual devel- opment was initiated in 1973. A major objective of the symposia has been to foster communication between the basic research worker and the clinical community. It is our feeling that much can be learned on both sides from this interaction. The idea for an informal meeting allowing maximum ex- change of ideas originated with Dr. Leon Candeub, who supplied the nec- essary driving force that made the series a reality. Each symposium has concentrated on a different aspect of ocular development. Speakers have been selected to approach related topics from different perspectives.
Table of Contents
Contents: Fibrils, Fibonacci, and Fractals: Searching for Rules and Rulers of Morphogenesis in the Orthogonal Stroma of the Chick Cornea.- The Role of Matrix Components in the Control of Vascularization.- Elucidation of the Visual Cycle by Study of Two Retinoid-Binding Proteins.- Roles of Intra- and Extracellular Retinoid-Binding Proteins in the Visual Cycle.- Vitamin A and Lipofuscin.- Reactive Oxygen Species-Toxicity, Metabolism, and Reactions in the Eye.- Light Damage.- Studies on Biochemical Mechanisms of Retinal Degeneration.- Environmental Factors in Cataractogenesis in RCS Rats.- Current Status of Vitamin E in Retinopathy of Prematurity.- Epidemiology of Age-Related Macular Degeneration.- Index.