Synopses & Reviews
World Health Organization data documents that infectious diseases and immunodeficiencies are the leading causes of morbidity and mortality in the world's children. In The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes, an authoritative, international panel of experts provide a succinct, up-to-date, evidence-based reference to the neurological consequences of infectious diseases and immunodeficiency syndromes in children in one readily accessible volume. Within each of its conveniently structured chapters, readers will find a general description of the disease or disorder, its epidemiology, etiology, clinical synopsis, neurological manifestations, diagnosis, differential diagnosis and therapy. Comprehensive yet concise, The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes is an ideal guide for pediatricians, primary care physicians and subspecialists to the complex relationships between infectious diseases, immunodeficiency syndromes and the neurological process.
Review
From the reviews: "This book addresses the neurologic emergencies of pediatric infections and immunodeficiencies in a logical, consistent fashion. ... It is written for physicians in training, primary care physicians, and subspecialists. Anyone treating or aspiring to treat ill children will profit this book. ... The consistent chapter organization is helpful. There is no comparable book and this one is welcome and useful. Neurologists will be better educated about infection ... . As a neurologist, I will open this book frequently." (John Willis, Doody's Review Service, September, 2008) "The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes is a carefully devised text with extensive coverage of topic. ... This book is written for physicians in training, primary health care physicians, subspecialists. ... The chapters are interesting to read. ... I would encourage any clinician who is actively involved in the treatment of children with neuroinfections to acquire this text as an essential part of their library." (Jo M. Wilmshurst, Clinical Infectious Diseases, Vol. 49 (1), January, 2009)
Synopsis
A major portion of all of acute child neurology involves the neurological complications of infectious diseases. However, none of the currently available excellent texts on inf- tious disease focus specifically on the neurological aspects. Drs. Neil R. Friedman and Leslie L. Barton have filled this important void with a superb, multi-authored text, addressing directly the neurological manifestations of pediatric infectious diseases and immunodeficiency syndromes. The book is organized logically according to the responsible microorganisms and addresses sequentially a broad spectrum of viruses, bacteria, fungi, rickettsiae, spirochetes, mycobacteriae, and parasites, as well as cat-scratch disease and human immunodeficiency virus (HIV) infection. The chapters are consistently similar in organization and begin with an introduction that provides a synopsis and perspective. The substance of the chapters follows in sections devoted to epidemiology, pathog- esis, clinical manifestations, diagnosis, treatment, and references. The discussions of epidemiology are particularly informative and current. The sections on pathogenesis include valuable neuropathology and critical distinctions among disorders caused by primary infection by the microorganism and those related to parainfectious and postinfectious immunological phenomena. The sections on clinical manifestations emphasize the neurological features and often are subdivided into specific neurolo- cal syndromes. Results of modern brain imaging are illustrated, and tables highlight neurological and other features. Sections on diagnosis are especially valuable and emphasize the value of polymerase chain reaction (PCR) and related means of identifying microbial nucleic acids and proteins. The discussions of treatment are especially current and valuable."
Synopsis
World Health Organization data documents that infectious diseases and immunodeficiencies are the leading causes of morbidity and mortality in the world's children. In this volume, an authoritative, international panel of experts provide a succinct, up-to-date, evidence-based reference to the neurological consequences of infectious diseases and immunodeficiency syndromes in children in one readily accessible volume. Within each of its conveniently structured chapters, readers will find a general description of the disease or disorder, its epidemiology, etiology, clinical synopsis, neurological manifestations, diagnosis, differential diagnosis and therapy. This book fills an important void and finally provides a volume for pediatricians, neurologists, infectious disease specialists and all who care for children.
Synopsis
In this concise book, an international panel of experts provide a succinct, up-to-date, evidence-based reference to the neurological consequences of infectious diseases and immunodeficiency syndromes in children in one readily accessible volume. Within each of its conveniently structured chapters, readers will find a general description of the disease or disorder. Finally a volume for pediatricians, neurologists, infectious disease specialists and all who care for children.
Table of Contents
TABLE OF CONTENTS Section 1: Viruses Chapter 1: Herpesviruses Sean Elliott, MD Herpes Simplex Virus Cytomegalovirus Varicella-Zoster Virus Epstein-Barr Virus Human Herpesviruses 6 and 7 Chapter 2: Myxoviruses Jason G. Newland, MD and José R. Romero, MD Paramyxoviruses Parainfluenza Viruses Mumps Virus Measles Virus Nipah and Hendra Viruses Orthomyxoviruses Influenza Viruses Chapter 3: Picornaviruses Motasem A. Abuelreish, MD and Mobeen H. Rathore, MD Enteroviruses Poliovirus Nonpolio Enteroviruses Coxsackivirus Echovirus Newer Enteroviruses Chapter 4: Arboviruses José R. Romero, MD Flaviviruses Saint Louis Encephalitis Virus West Nile Virus Powassan Encephalitis Virus Bunyaviruses La Crosse Encephalitis Virus California Encephalitis Virus Jamestown Canyon Virus Snowshoe Hare Virus Trivittatus Virus Keystone Virus Chapter 5: Togaviruses José R. Romero, MD, Meera Varman, MD and Leslie Barton, MD Alphaviruses Eastern Equine Encephalitis Virus Western Equine Encephalitis Virus Rubella Virus Chapter 6: Rhabdoviruses Rabies Virus Chapter 7: Adenoviruses Allan D. Friedman, MD, MPH and Sean O. McKenna, MD Chapter 8: Arenaviruses Daniel J. Bonthius, MD, PhD, Leslie Barton, MD, Hannah Klein de Licona, Nancy E. Bonthius, Pharm D, and Bahri Karacay, PhD. Lymphocytic Choriomeningitis Virus Miscellaneous Hemorrhagic Fevers Chapter 9: Orthopoxviruses José R. Romero, MD Smallpox Chapter 10: Retroviruses Lemuel Aigbivbalu, M.D, Ayesha Mirza, MD and Mobeen H. Rathore, MD. Human Immunodeficiency Virus Chapter 11: Neurological Consequences of Antiretroviral Treatment Kimberley C. Brown, Pharm.D., Lisa D. Inge, Pharm.D., Mobeen H. Rathore, MD Chapter 12: Papovaviruses Diane Halstead, Ph.D. and Mobeen H. Rathore, M.D. Polyomaviruses (JC Virus) Section 2: Bacteria Chapter 13: Bacterial meningitis Barbara Stechenberg, MD Chapter 14: Focal Bacterial Infections and Parameningeal Infections Barbara Stechenberg, MD Brain abscess Subdural empyema Epidural abscesses Chapter 15: Streptococcus pyogenes Barbara Stechenberg, MD Acute rheumatic fever Chapter 16: Bordetella pertussis Barbara Stechenberg, MD Pertussis Chapter 17: Shigella species Barbara Stechenberg, MD Shigellosis Chapter 18: Campylobacter species Barbara Stechenberg, MD Chapter 19: Brucella species Barbara Stechenberg, MD Brucellosis Chapter 20 : Clostridium tetani Barbara Stechenberg, MD Tetanus Chapter 21: Clostridium botulinum Barbara Stechenberg, MD Botulism Chapter 22: Corynebacterium diphtheriae Barbara Stechenberg, MD Diptheria Chapter 23: Bartonella species Andrew M. Margileth, MD and Mobeen Rathore, MD Cat Scratch Disease Chapter 24: Mycobacterium tuberculosis Barbara Stechenberg, MD Tuberculosis Chapter 25: Mycobacterium leprae Barbara Stechenberg, MD Leprosy Section 3: Rickettsia and Spirochetes Chapter 26: Rickettsia rickettsii Abeer Khayat, MD and Mobeen H. Rathore, MD Rocky Mountain Spotted Fever Chapter 27: Ehrlichia and Anaplasma species Abeer Khayat, MD and Mobeen Rathore, MD Human monocytotropic ehrlichiosis Human granulocytotropic anaplasmosis Chapter 28: Borrelia burgdorferi Abeer Khayat, MD and Mobeen Rathore, MD Lyme Disease Chapter 29: Treponema pallidum Abeer Khayat, MD and Mobeen H. Rathore, MD Syphilis Section 4 : Fungi Chapter 30: Candida species Barbara Stechenberg, MD Candidiasis Chapter 31: Cryptococcus neoformans Barbara Stechenberg, MD Cryptococcosis Chapter 32: Histoplasma capsulatum Barbara Stechenberg, MD Histoplasmosis Chapter 33: Coccidioides species Barbara Stechenberg, MD Coccidioidomycosis Chapter 34: Phaeohyphomycoses Barbara Stechenberg, MD Section 5: Protozoa Chapter 35: Protozoal Infections Ana M. Alvarez, MD and Mobeen H. Rathore, MD Toxoplasma gondii Toxoplasmosis Plasmodium species Malaria Entamoeba histolytica Amebiasis Naegleria, Acanthamoeba, and Balamuthia species Amebic meningoencephalitis Trypanosoma species African Trypanosomiasis American Trypanosomiasis (Chagas disease) Chapter 36: Babesia species Abeer Khayat, MD and Mobeen H. Rathore, MD Babesiosis Section 6: Helminths Chapter 37: Helminth infections Patrick J. Gavin, MB Cestodes Taenia species Neurocysticercosis Coenurosis Echinococcus species Hydatid disease (Echinococcosis) Spirometra species Sparganosis Nematodes Angiostrongylus cantonensis Angiostrongyliasis Toxocara species Toxocariasis Baylisascaris procyonis Baylisascariasis Trichinella spiralis Trichinosis Strongyloides stercoralis Strongyloidiasis Ganthostoma spinigerum Gnathostomiasis Trematodes Schistosoma species Schistosomiasis Paragonimus species Paragonimiasis Section 7: Primary Immunodeficiencies Chapter 38: Neurological Disease and Primary Immunodeficiency Megan Connick, MD Ataxia-telangectasia Nijmegen breakage syndrome X-linked agammaglobulinemia Chronic granulomatous disease Chédiak-Higashi syndrome Griscelli syndrome Purine nucleoside phosphorylase deficiency Section 8: Basic Principles of Selective Neurological Treatments Chapter 39: Basic Principles of Selective Neurological Treatments Neil R. Friedman, MBChB and Manikum Moodley, MBChB Supportive care Seizures Raised intracranial pressure