Synopses & Reviews
An up-to-date review of an important area in microbiology.
Review
"...well written and provides a review on the latest research in the area, with extensive references abailable to the reader. The tables and figures presented in Transport of Molecules Across Microbial Membranes could be valuable learning tools for students and instructors." Canadian Society of Microbiologists
Synopsis
This volume details the transport of molecules, large and small, across the membranes of prokaryotic and eukaryotic microbial cells. An international group of contributors unify a diverse range of phenomena with the discussion of the signal peptides that target proteins to particular destinations, and the role of chaperonins. Topics covered include secretion of proteins out of the bacterial cell by Type I, II, and III mechanisms, including the newly recognized bacterial signal recognition pathway in Type II; passage across internal membranes of eukaryotic proteins, whether destined for secretion or en route to internal organelles such as chloroplasts and peroxisomes; how bacteria obtain energy required for solute uptake; the role of phosphorylation and evolutionary relationships of the proteins involved; and efflux pumps for toxic substances in bacterial, animal, and plant cells.
Synopsis
This book describes, at the molecular level, some of the most important ways in which microbes move substances that they make, or that they encounter in their environment, from one place to another.
Table of Contents
Preface; 1. Overview: transport of molecules across microbial membranes - a sticky business to get to grips with J. K. Broome-Smith and C. Mitsopoulos; 2. Multidrug resistance efflux K. Lewis; 3. Regulation of solute accumulation in bacteria and its physiological significance B. Poolman; 4. Arsenic transport systems from Escherichia coli to humans H. Bhattacharjee, M. Ghosh, R. Mukhopadhyay and B. P. Rosen; 5. Type II protein secretion: the main terminal branch of the general secretory pathway A. Filloux; 6. Type III secretion and the pathogenesis of Yersinia infections D. M. Anderson, L. W. Cheng, V. T. Lee, S. Masmanian, K. Ramamurthi, C. Tam and O. Schneewind; 7. Assembly of bacterial adhesins across the outer membrane via the chaperone-usher pathway G. E. Soto and S. J. Hultgren; 8. DNA uptake by transformable bacteria S. A. Lacks; 9. Escherichia coli signal recognition particle - a historical perspective Q. A. Valent, E. N. S. O'Gorman, P. Scotti, J. Luirink and S. High; 10. Protein translocation into the endoplasmic reticulum B. P. Young, J. K. Brownsword and C. J. Stirling; 11. Peroxisome biogenesis E. Lopez-Huertas and A. Baker; 12. Transport of proteins into and across the thylakoid membrane C. Robinson, W. Edwards, P. J. Hynds and C. Tissier; 13. Evolutionary origins of transmembrane transport systems M. H. Saier Jr and T.-T. Tseng; Index.